Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFC0026)
HIF Name
Peripheral blood mononuclear cells
HIF Synonym(s)
PBMC, Peripheral blood mononuclear cell
HIF Classification
Monocytes (Mono)
Description Peripheral blood mononuclear cell is any peripheral blood cell having a round nucleus. These cells consist of lymphocytes (T cells, B cells, NK cells) and monocytes, whereas erythrocytes and platelets have no nuclei, and granulocytes (neutrophils, basophils, and eosinophils) have multi-lobed nuclei. [1]
Microbe Species (MIC) Regulated by This HIF
         Methanomassiliicoccus luminyensis (euryarchaeotes) MIC00800
             Description Methanomassiliicoccus luminyensis could led to the release of peripheral blood mononuclear cells (PBMC). [2]
         Parascardovia denticolens (actinobacteria) MIC00858
             Description Peripheral blood mononuclear cells from subjects with past or current Mycobacterium ulcerans disease showed significantly reduced proliferation. [3]
         Veillonella parvula (firmicutes) MIC01365
             Description Veillonella parvula lipopolysaccharide stimulated tumor necrosis factor alpha (TNF-alpha) and interleukin-6 (IL-6) release in human peripheral blood mononuclear cells (PBMC) in a dose-dependent manner. [4]
References
1 T Cell: Primary Culture from Peripheral Blood.Methods Mol Biol. 2019;2020:17-31. doi: 10.1007/978-1-4939-9591-2_2.
2 Immunogenic properties of the human gut-associated archaeon Methanomassiliicoccus luminyensis and its susceptibility to antimicrobial peptides. PLoS One. 2017 Oct 5;12(10):e0185919. doi: 10.1371/journal.pone.0185919. eCollection 2017.
3 Immune response to infection with Mycobacterium ulcerans. Infect Immun. 2001 Mar;69(3):1704-7. doi: 10.1128/IAI.69.3.1704-1707.2001.
4 Receptor recognition of and immune intracellular pathways for Veillonella parvula lipopolysaccharide. Clin Vaccine Immunol. 2009 Dec;16(12):1804-9. doi: 10.1128/CVI.00310-09. Epub 2009 Oct 14.

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