| General Information of MIC (ID: MIC00858) |
| MIC Name |
Parascardovia denticolens (actinobacteria)
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| Body Site |
Skin
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| Lineage |
Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinobacteria
Order: Corynebacteriales
Family: Mycobacteriaceae
Genus: Mycobacterium
Species: Mycobacterium ulcerans
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| Oxygen Sensitivity |
Aerobe
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| Gram |
Positive
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| Host Relationship |
Pathogen
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| Description |
Mycobacterium ulcerans is a slow-growing mycobacterium that classically infects the skin and subcutaneous tissues, giving rise to indolent nonulcerated and ulcerated lesions.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| GOLD Organism ID |
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| Host Genetic Factors (HGFs) |
| rs17235409 |
| HGF ID |
HGF1353 |
HGF Info
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Class |
Single Nucleotide Polymorphism: Missense variant (SNP-MV) |
| Description |
The rs17235409 SNP tended to be associated with Mycobacterium ulcerans infection. |
[1] |
| rs1333955 |
| HGF ID |
HGF1439 |
HGF Info
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Class |
Single Nucleotide Polymorphism: Intron variant (SNP-IV) |
| Description |
The rs1333955 SNP tended to be associated with Mycobacterium ulcerans infection. |
[1] |
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| Host Immune Factors (HIFs) |
| Interferon gamma |
| HIF ID |
HIFM0260 |
HIF Info
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Class |
Cytokine (Cyt) |
| Description |
The abundance of Mycobacterium ulcerans is associated with IFN-Gamma. |
[2] |
| Immunoglobulin G2 |
| HIF ID |
HIFM0268 |
HIF Info
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Class |
Immunoglobulin (Ig) |
| Description |
The abundance of Mycobacterium ulcerans is associated with IgG2 response. |
[2] |
| Peripheral blood mononuclear cells |
| HIF ID |
HIFC0026 |
HIF Info
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Class |
Monocytes (Mono) |
| Description |
Peripheral blood mononuclear cells from subjects with past or current Mycobacterium ulcerans disease showed significantly reduced proliferation. |
[2] |
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| Environmental Factor(s) |
| Disbiome ID |
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| References |
| 1 |
Susceptibility to Mycobacterium ulcerans Disease (Buruli ulcer) Is Associated with IFNG and iNOS Gene Polymorphisms.Front Microbiol. 2017 Oct 4;8:1903. doi: 10.3389/fmicb.2017.01903. eCollection 2017.
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| 2 |
Immune response to infection with Mycobacterium ulcerans. Infect Immun. 2001 Mar;69(3):1704-7. doi: 10.1128/IAI.69.3.1704-1707.2001.
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