General Information of HIF (ID: HIFC0082)
HIF Name	T helper type 1 cells
HIF Synonym(s)	Th1, T helper type 1(Th1) cells
HIF Classification	T cells (TCs)
Description	T helper type 1(Th1)cellsare a subset of CD4 + effectorT cellsthat is required for host defense against intracellular viral and bacterial pathogens.				[1]

Microbe Species (MIC) Regulated by This HIF
Listeria monocytogenes (firmicutes)			MIC00771
Description	Listeria monocytogenes-specific T cells were shown to differentiate into T helper type 1(Th1)cells.				[2]
Salmonella enterica subsp. enterica (enterobacteria)			MIC01154
Description	Salmonella typhimurium infection resulted in T helper type 1 (Th1) cells in diabetes mellitus patients.				[2]

References
1	Tail domains of myosin-1e regulate phosphatidylinositol signaling and F-actin polymerization at the ventral layer of podosomes.Mol Biol Cell. 2019 Mar 1;30(5):622-635. doi: 10.1091/mbc.E18-06-0398. Epub 2019 Jan 2.
2	Microbiota in T-cell homeostasis and inflammatory diseases.Exp Mol Med. 2017 May 26;49(5):e340. doi: 10.1038/emm.2017.36.

If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.