General Information of HIF (ID: HIFC0220)
HIF Name	IgM plasma B cell
HIF Synonym(s)	IgM plasma cell
HIF Classification	B cells (BCs)
Description	IgM plasma cell is a type of the immune cells.				[1]

Microbe Species (MIC) Regulated by This HIF
Dengue virus (viruses)			MIC02008
Description	IgM plasma cell response was associated with the expression of Dengue virus.				[2]
Leishmania infantum (kinetoplastids)			MIC01797
Description	IgM plasma cells were present in the marginal zones and periarteriolar areas in the spleens of Visceral leishmaniasis caused by Leishmania infantum.				[3]
Leishmania major (kinetoplastids)			MIC01993
Description	Leishmania stimulated B-cells to differentiate into short-lived IgM plasma cells with limited lifespan in the medullar cords of lymph nodes and splenic red pulp in the primary immune response.				[3]
Plasmodium vivax (apicomplexans)			MIC01998
Description	Plasmodium spp. stimulated B-cells to differentiate into short-lived IgM plasma cells with limited lifespan in the medullar cords of lymph nodes and splenic red pulp in the primary immune response.				[3]

References
1	A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues.PLoS One. 2016 Mar 3;11(3):e0150606. doi: 10.1371/journal.pone.0150606. eCollection 2016.
2	Total and Envelope Protein-Specific Antibody-Secreting Cell Response in Pediatric Dengue Is Highly Modulated by Age and Subsequent Infections.PLoS One. 2016 Aug 25;11(8):e0161795. doi: 10.1371/journal.pone.0161795. eCollection 2016.
3	Disruption of Splenic Lymphoid Tissue and Plasmacytosis in Canine Visceral Leishmaniasis: Changes in Homing and Survival of Plasma Cells.PLoS One. 2016 May 31;11(5):e0156733. doi: 10.1371/journal.pone.0156733. eCollection 2016.

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