Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFM0021)
HIF Name
C-C motif chemokine 19
HIF Synonym(s)
C-C motif chemokine ligand 19, CKb11, ELC, MIP-3b, MIP3B, SCYA19
HIF Classification
Cytokine (Cyt)
Molecular Function
Cytokine
Description Chemokines were originally described as cytokines that mediate leukocyte recruitment to sites of inflammation [1]
Pfam Small cytokines (intecrine/chemokine), interleukin-8 like (PF00048 )
Pathway Chemokine signaling pathway (hsa04062 )
Cytokine-cytokine receptor interaction (hsa04060 )
NF-kappa B signaling pathway (hsa04064 )
Viral protein interaction with cytokine and cytokine receptor (hsa04061 )
Sequence Click here to download the HIF sequence in FASTA format
External Links
Uniprot ID
CCL19_HUMAN
Microbe Species (MIC) Regulated by This HIF
         Bifidobacterium pseudolongum (actinobacteria) MIC00220
             Description Stimulation of DC and macrophage lines with Bifidobacterium pseudolongum induced the homeostatic chemokine CCL19. [2]
         Staphylococcus aureus (firmicutes) MIC01208
             Description The CCL19 signaling pathway activation was influenced among proinflammatory factors by Staphylococcus aureus. [3]
References
1 CCL19 and CCR7 Expression, Signaling Pathways, and Adjuvant Functions in Viral Infection and Prevention.Front Cell Dev Biol. 2019 Oct 1;7:212. doi: 10.3389/fcell.2019.00212. eCollection 2019.
2 Gut microbiota-dependent modulation of innate immunity and lymph node remodeling affects cardiac allograft outcomes. JCI Insight. 2018 Oct 4;3(19):e121045. doi: 10.1172/jci.insight.121045.
3 Microbe-host interplay in atopic dermatitis and psoriasis.Nat Commun. 2019 Oct 16;10(1):4703. doi: 10.1038/s41467-019-12253-y.

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