General Information of HIF (ID: HIFM0206)
HIF Name	Human calcitermin
HIF Synonym(s)	Human Calcitermin, S100A12
HIF Classification	Antimicrobial peptide (AMP)
Molecular Function	Antibiotic; Antimicrobial; Fungicide
Description	Human Calcitermin has been identified in humans. It forms the first line of host defense against pathogenic infections and are a key component of the ancient innate immune system.				[1]
Pfam	S-100/ICaBP type calcium binding domain (PF01023 )
Sequence	Click here to download the HIF sequence in FASTA format
External Links
	Uniprot ID	S10AC_HUMAN
	APD ID	AP00507

Microbe Species (MIC) Regulated by This HIF
Candida albicans (budding yeasts)			MIC00317
Description	The concentration of Calcitermin(50ug/ml) was active against Candida albicans.				[2]
Escherichia coli (enterobacteria)			MIC00516
Description	Calcitermin of 50ug/ml had inhibitory activity against Escherichia coli.				[2]
Pseudomonas aeruginosa (gamma-proteobacteria)			MIC01054
Description	The concentration of Calcitermin(50ug/ml) was active against Pseudomonas aeruginosa.				[2]

References
1	APD3: the antimicrobial peptide database as a tool for research and education.Nucleic Acids Res. 2016 Jan 4;44(D1):D1087-93. doi: 10.1093/nar/gkv1278. Epub 2015 Nov 23.
2	Calcitermin, a novel antimicrobial peptide isolated from human airway secretions.FEBS Lett. 2001 Aug 24;504(1-2):5-10. doi: 10.1016/s0014-5793(01)02731-4.

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