General Information of HIF (ID: HIFM0290)
HIF Name	HD-5(7-32)
HIF Synonym(s)	Hd-5(7-32)
HIF Classification	Antimicrobial peptide (AMP)
Description	HD-5(7-32) has been identified in humans. It forms the first line of host defense against pathogenic infections and are a key component of the ancient innate immune system.				[1]
External Links
	APD ID	AP03065

Microbe Species (MIC) Regulated by This HIF
Akkermansia sp. (verrucomicrobia)			MIC00057
Description	HD-5732 could preserve the selective increase of Akkermansia sp..				[2]
Helicobacter bilis (epsilon-proteobacteria)			MIC00663
Description	HD-5732 could specifically diminish Helicobacter abundance.				[2]

References
1	APD3: the antimicrobial peptide database as a tool for research and education.Nucleic Acids Res. 2016 Jan 4;44(D1):D1087-93. doi: 10.1093/nar/gkv1278. Epub 2015 Nov 23.
2	Paneth cell -defensins HD-5 and HD-6 display differential degradation into active antimicrobial fragments.Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3746-3751. doi: 10.1073/pnas.1817376116. Epub 2019 Feb 11.

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