Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00166)
MIC Name Prevotella oralis (CFB bacteria)
MIC Synonyms Ristella oralis
Body Site Skin
Lineage Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidia
Order: Bacteroidales
Family: Prevotellaceae
Genus: Prevotella
Species: Prevotella oralis
Oxygen Sensitivity Anaerobe
Microbial Metabolism Fermentative; Respiratory
Gram Negative
Host Relationship Commensal
Genome Size (bp) 2836154
Description It is an obligate anaerobic, non-motile, non-spore forming and non-pigmenting organisms that has mostly been found in gingival crevices of the human mouth. It has been shown to grow within biofilms as part of a healthy oral fauna in humans, but is also capable of being a facultative pathogen.
External Links Taxonomy ID
28134
Genome Assembly ID
ASM18514v2
GOLD Organism ID
Go0005350
Disease Relevance
          Autism spectrum disorder  [ICD-11: 6A02]
             Description Prevotella oris was significantly elevated in autistic children. [1]
          Dental caries  [ICD-11: DA08]
             Description Prevotella oris which is one of the periodontopathogens, are frequently detected in severe forms of periodontal diseases. [2]
          Meningococcal disease  [ICD-11: 1C1C]
             Description Prevotella oris can induce bacteraemia. [3]
          Obesity  [ICD-11: 5B81]
             Description Prevotella oris was associated with genetic variants in Obesity. [4]
          Periodontal disease  [ICD-11: DA0C]
             Description The coaggregation of Prevotella oris and Prevotella gingivalis may contribute to the initiation and progression of periodontitis. [2]
          Rheumatoid arthritis  [ICD-11: FA20]
             Description Prevotella oris were associated with early RA(rheumatoid arthritis) independent of severity of periodontitis. [5]
Host Immune Factors (HIFs)
          Immunoglobulin M
             HIF ID HIFM0266 HIF Info       Class Immunoglobulin (Ig)
             Description The abundance of Prevotella oralis is associated with IgM response. [6]
          Immunoglobulin G
             HIF ID HIFM0270 HIF Info       Class Immunoglobulin (Ig)
             Description The abundance of Prevotella oralis is associated with IgG immune response. [6]
Environmental Factor(s)
             Disbiome ID
      281
             gutMDisorder ID
      gm0535
References
1 The Possible Role of the Microbiota-Gut-Brain-Axis in Autism Spectrum Disorder. Int J Mol Sci. 2019 Apr 29;20(9):2115. doi: 10.3390/ijms20092115.
2 Coaggregation between Prevotella oris and Porphyromonas gingivalis. J Microbiol Immunol Infect. 2014 Jun;47(3):182-6. doi: 10.1016/j.jmii.2012.09.005. Epub 2012 Dec 12.
3 Bacteremia and sepsis due to Prevotella oris from dentoalveolar abscesses. Intensive Care Med. 2003 May;29(5):856. doi: 10.1007/s00134-003-1697-z. Epub 2003 Mar 28.
4 M-GWAS for the gut microbiome in Chinese adults illuminates on complex diseases. bioRxiv, 2019.
5 FRI0698 Prevotella and alloprevotella species characterize the oral microbiome of early rheumatoid arthritis[J]. Annals of the Rheumatic Diseases, 2017: 754-754.
6 Immune response in rats against lipopolysaccharides of Fusobacterium nucleatum and Bacteroides oralis administered in the root canal. Scand J Dent Res. 1980 Apr;88(2):122-9. doi: 10.1111/j.1600-0722.1980.tb01203.x.

If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.