Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00313)
MIC Name Campylobacter rectus (epsilon-proteobacteria)
MIC Synonyms Wolinella recta
Body Site Oral Cavity
Lineage Kingdom: Bacteria
Phylum: Proteobacteria
Class: Epsilonproteobacteria
Order: Campylobacterales
Family: Campylobacteraceae
Genus: Campylobacter
Species: Campylobacter rectus
Oxygen Sensitivity Facultative anaerobe; Microaerophile
Microbial Metabolism Asaccharolytic; Nonfermentative
Gram Negative
Genome Size (bp) 2513107
Description Campylobacter rectus is a facultatively anaerobic or microaerophilic, Gram negative, motile bacterium of Campylobacter. It is implicated as a pathogen in chronic periodontitis, which can induce bone loss. C. rectus is associated with hypertension together with Prevotella melaninogenica and Veillonella parvula.
External Links Taxonomy ID
203
Genome Assembly ID
ASM17417v1
GOLD Organism ID
Go0003989
Disease Relevance
          Periodontal disease  [ICD-11: DA0C]
             Description Campylobacter rectus was associated with chronic periodontitis. [1]
Host Genetic Factors (HGFs)
          rs6940
             HGF ID HGF1734 HGF Info       Class Single Nucleotide Polymorphism: Missense variant (SNP-MV)
             Description Haplotype blocks rs6940 was ignificantly associated with increased extent bleeding on probing and levels of microorganisms Campylobacter rectus (p0.05). [2]
          rs1057028
             HGF ID HGF1735 HGF Info       Class Single Nucleotide Polymorphism: Missense variant (SNP-MV)
             Description Haplotype blocks rs1057028 was ignificantly associated with increased extent bleeding on probing and levels of microorganisms Campylobacter rectus (p0.05). [2]
Host Immune Factors (HIFs)
          Immunoglobulin G
             HIF ID HIFM0270 HIF Info       Class Immunoglobulin (Ig)
             Description IgG immune responses is associated with Campylobacter rectus. [3]
          Toll-like receptor 4
             HIF ID HIFM0219 HIF Info       Class Toll-like receptor (TLR)
             Description TLR4 mediated intrauterine growth restriction after systemic Campylobacter rectus infection. [4]
Environmental Factor(s)
             Disbiome ID
      363
             gutMDisorder ID
      gm0142
References
1 Periopathogens in atherosclerotic plaques of patients with both cardiovascular disease and chronic periodontitis. ARYA Atheroscler. 2018 Mar;14(2):53-57. doi: 10.22122/arya.v14i2.1504.
2 Common Polymorphisms in IFI16 and AIM2 Genes Are Associated With Periodontal Disease.J Periodontol. 2017 Jul;88(7):663-672. doi: 10.1902/jop.2017.160553. Epub 2017 Apr 7.
3 Serum IgG antibody levels to periodontal microbiota are associated with incident Alzheimer disease.PLoS One. 2014 Dec 18;9(12):e114959. doi: 10.1371/journal.pone.0114959. eCollection 2014.
4 Toll-like receptor 4 mediates intrauterine growth restriction after systemic Campylobacter rectus infection in mice. Mol Oral Microbiol. 2012 Oct;27(5):373-81. doi: 10.1111/j.2041-1014.2012.00651.x. Epub 2012 Jun 9.

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