| General Information of MIC (ID: MIC00443) |
| MIC Name |
Coprococcus eutactus (firmicutes)
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| Body Site |
Gut
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| Lineage |
Kingdom: Bacteria
Phylum: Firmicutes
Class: Clostridia
Order: Clostridiales
Family: Lachnospiraceae
Genus: Coprococcus
Species: Coprococcus eutactus
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| Oxygen Sensitivity |
Obligate anaerobe
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| Microbial Metabolism |
Saccharolytic; Fermentative
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| Gram |
Positive
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| Host Relationship |
Commensal
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| Genome Size (bp) |
3102087
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| Description |
Coprococcus eutactus is an obligately anaerobic, Gram positive bacterium of the genus Coprococcus.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| GOLD Organism ID |
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| Disease Relevance |
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| Parkinsonism [ICD-11: 8A00] |
| Description |
Coprococcus eutactus was reduced in patients with parkinsons disease. |
[1] |
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| Host Genetic Factors (HGFs) |
| NOD2 |
| HGF ID |
HGF2335 |
HGF Info
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Class |
Copy Number Variation: Gene Deletion (CNV-GDe) |
| Description |
The deletion of NOD2 showed significantly increased abundance of Coprococcus eutactus (p-value<0.05). |
[2] |
| rs709149 |
| HGF ID |
HGF1406 |
HGF Info
|
Class |
Single Nucleotide Polymorphism: Intron variant (SNP-IV) |
| Description |
The variant gene PPAR of innate immunity rs709149 is significantly associated with the abundance of gut micriobiota Coprococcus eutactus (p-value=0.0131). |
[3] |
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| Host Immune Factors (HIFs) |
| Immunoglobulin E |
| HIF ID |
HIFM0271 |
HIF Info
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Class |
Immunoglobulin (Ig) |
| Description |
Coprococcus eutactus is negatively associated with IgE level. |
[4] |
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| Environmental Factor(s) |
| Disbiome ID |
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| gutMDisorder ID |
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| References |
| 1 |
Analysis of Gut Microbiota in Patients with Parkinson's Disease. Bull Exp Biol Med. 2017 Apr;162(6):734-737. doi: 10.1007/s10517-017-3700-7. Epub 2017 Apr 20.
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| 2 |
Nod2 and Nod2-regulated microbiota protect BALB/c mice from diet-induced obesity and metabolic dysfunction.Sci Rep. 2017 Apr 3;7(1):548. doi: 10.1038/s41598-017-00484-2.
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| 3 |
Variants in genes of innate immunity, appetite control and energy metabolism are associated with host cardiometabolic health and gut microbiota composition.Gut Microbes. 2020 May 3;11(3):556-568. doi: 10.1080/19490976.2019.1619440. Epub 2019 Jun 3.
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| 4 |
Impact of a 3-Months Vegetarian Diet on the Gut Microbiota and Immune Repertoire.Front Immunol. 2018 Apr 27;9:908. doi: 10.3389/fimmu.2018.00908. eCollection 2018.
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