Details of Host Genetic Factor (HGF) Regulating Microbe Species (MIC)

General Information of HGF (ID: HGF2335)
HGF Name NOD2
HGF Synonym(s) CD, ACUG, BLAU, IBD1, YAOS, BLAUS, NLRC2, NOD2B, CARD15, CLR16.3, PSORAS1, nucleotide binding oligomerization domain containing 2
Source Homo sapiens
HGF Classification Copy Number Variation: Gene Deletion (CNV-GDe)
Gene Location chr16
Gene Start Site 50693588 Gene End Site 50734041
Strand Forward (+)
External Links
Ensembl ID
ENSG00000167207
Microbe Species (MIC) Regulated by This HGF
         Adlercreutzia equolifaciens (actinobacteria) MIC00042
             Description The deletion of NOD2 showed significantly increased abundance of Adlercreutzia equolifaciens (p-value<0.05). [1]
         Bacillus mycoides (firmicutes) MIC01442
             Description The deletion of NOD2 has been associated with the increased amount of Bacillus. [2]
         Bacteroides sp. (CFB bacteria) MIC00176
             Description The deletion of NOD2 showed significantly increased abundance of Bacteroides sp. (p-value<0.05). [1]
         Blautia obeum (firmicutes) MIC00240
             Description The deletion of NOD2 showed significantly increased abundance of Blautia obeum (p-value<0.05). [1]
         Butyricimonas sp. (CFB bacteria) MIC01928
             Description The deletion of NOD2 showed significantly increased abundance of Butyricimonas sp. (p-value<0.05). [1]
         Coprococcus catus (firmicutes) MIC00441
             Description The deletion of NOD2 showed significantly increased abundance of Coprococcus catus (p-value<0.05). [1]
         Coprococcus eutactus (firmicutes) MIC00443
             Description The deletion of NOD2 showed significantly increased abundance of Coprococcus eutactus (p-value<0.05). [1]
         Eubacterium rectale (firmicutes) MIC00578
             Description The deletion of NOD2 increased the abundance of Eubacterium rectale. (p-value<0.05). [1]
         Flexistipes (bacteria) MIC01929
             Description The deletion of NOD2 showed significantly increased abundance of Flexistipes sp. (p-value<0.05). [1]
         Helicobacter ganmani (epsilon-proteobacteria) MIC01930
             Description The deletion of NOD2 showed significantly increased abundance of Helicobacter ganmani (p-value<0.05). [1]
         Hydrogenoanaerobacterium saccharovorans (firmicutes) MIC01966
             Description The deletion of NOD2 showed significantly increased abundance of Hydrogenoanaerobacterium sp. (p-value<0.05). [1]
         Lachnoclostridium (firmicutes) MIC01882
             Description The deletion of NOD2 showed significantly increased abundance of Lachnoclostridium (p-value<0.05). [1]
         Listeria monocytogenes (firmicutes) MIC00771
             Description The deletion of NOD2 has been associated with the increased amount of Listeria. [2]
         Mucispirillum sp. (bacteria) MIC00841
             Description The deletion of NOD2 increased the abundance of Mucispirillum sp. (p-value<0.05). [1]
         Rikenella sp. (CFB bacteria) MIC01927
             Description The deletion of NOD2 showed significantly increased abundance of Rikenella sp. (p-value<0.05). [1]
References
1 Nod2 and Nod2-regulated microbiota protect BALB/c mice from diet-induced obesity and metabolic dysfunction.Sci Rep. 2017 Apr 3;7(1):548. doi: 10.1038/s41598-017-00484-2.
2 Current understanding of the gut microbiota shaping mechanisms.J Biomed Sci. 2019 Aug 21;26(1):59. doi: 10.1186/s12929-019-0554-5.

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