| General Information of MIC (ID: MIC00841) |
| MIC Name |
Mucispirillum sp. (bacteria)
|
| Body Site |
Mucosa
|
| Lineage |
Kingdom: Bacteria
Phylum: Deferribacteres
Class: Deferribacteres
Order: Deferribacterales
Family: Deferribacteraceae
Genus: Mucispirillum
Species: Mucispirillum sp.
|
| Oxygen Sensitivity |
Obligate aerobe
|
| Microbial Metabolism |
Saccharolytic
|
| Gram |
Positive
|
| Host Relationship |
Pathogen
|
| Description |
Mucispirillum is a genus of family Deferribacteraceae.
|
| External Links |
Taxonomy ID |
|
| Disease Relevance |
|---|
| Non-alcoholic fatty liver disease [ICD-11: DB92] |
| Description |
Mucispirillum genus and Mucispirillum schaedleri species increased largely in subjects with nonalcoholic steatohepatitis. |
[1] |
|
|
|
|
|
|
| Host Genetic Factors (HGFs) |
| NOD2 |
| HGF ID |
HGF2335 |
HGF Info
|
Class |
Copy Number Variation: Gene Deletion (CNV-GDe) |
| Description |
The deletion of NOD2 increased the abundance of Mucispirillum sp. (p-value<0.05). |
[2] |
|
|
|
|
|
|
| Host Immune Factors (HIFs) |
| Tumor necrosis factor |
| HIF ID |
HIFM0226 |
HIF Info
|
Class |
Cytokine (Cyt) |
| Description |
Mucispirillum is associated with the level of TNFAlpha. |
[3] |
|
|
|
|
|
|
| Environmental Factor(s) |
| Disbiome ID |
|
|
|
|
|
|
|
| References |
| 1 |
Coordinated changes of gut microbiome and lipidome differentiates nonalcoholic steatohepatitis (NASH) from isolated steatosis. Liver Int. 2020 Mar;40(3):622-637. doi: 10.1111/liv.14316. Epub 2019 Dec 30.
|
| 2 |
Nod2 and Nod2-regulated microbiota protect BALB/c mice from diet-induced obesity and metabolic dysfunction.Sci Rep. 2017 Apr 3;7(1):548. doi: 10.1038/s41598-017-00484-2.
|
| 3 |
Altered gut microbiota and inflammatory cytokine responses in patients with Parkinson's disease. J Neuroinflammation. 2019 Jun 27;16(1):129. doi: 10.1186/s12974-019-1528-y.
|
If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.
