Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00621)
MIC Name Fusobacterium varium (fusobacteria)
MIC Synonyms Bacteroides varius
Body Site Gut
Lineage Kingdom: Bacteria
Phylum: Fusobacteria
Class: Fusobacteriia
Order: Fusobacteriales
Family: Fusobacteriaceae
Genus: Fusobacterium
Species: Fusobacterium varium
Oxygen Sensitivity Obligate anaerobe
Microbial Metabolism Saccharolytic; Fermentative; Proteolytic
Gram Negative
Host Relationship Commensal
Genome Size (bp) 3321664
Description Fusobacterium varium is an obligate anaerobe, Gram negative bacterium.
External Links Taxonomy ID
856
Genome Assembly ID
Fuso_varium_ATCC_27725_V2
GOLD Organism ID
Go0003599
Disease Relevance
          Ulcerative colitis  [ICD-11: DD71]
             Description Fusobacterium varium bacteria were present in a significant number of patients with active ulcerative colitis. [1]
Host Immune Factors (HIFs)
          Immunoglobulin G
             HIF ID HIFM0270 HIF Info       Class Immunoglobulin (Ig)
             Description The abundance of Fusobacterium varium is associated with IgG immune response. [2]
          Immunoglobulin A
             HIF ID HIFM0272 HIF Info       Class Immunoglobulin (Ig)
             Description The abundance of Fusobacterium varium is associated with IgA immune response. [2]
Environmental Factor(s)
             Disbiome ID
      270
             gutMDisorder ID
      gm0344
References
1 Fusobacterium varium localized in the colonic mucosa of patients with ulcerative colitis stimulates species-specific antibody. J Gastroenterol Hepatol. 2002 Aug;17(8):849-53. doi: 10.1046/j.1440-1746.2002.02834.x.
2 Investigation of the immune response to aerobic and anaerobic intestinal bacteria in a patient with Crohn's disease. Scand J Infect Dis Suppl. 1979;(19):52-60.

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