General Information of MIC (ID: MIC00712) |
MIC Name |
Lactobacillus delbrueckii (firmicutes)
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MIC Synonyms |
Bacillus Delbrucki
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Body Site |
Gut
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Lineage |
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Lactobacillaceae
Genus: Lactobacillus
Species: Lactobacillus delbrueckii
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Oxygen Sensitivity |
Anaerobe
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Microbial Metabolism |
Saccharolytic
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Gram |
Positive
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Host Relationship |
Probiotic
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Genome Size (bp) |
1856951
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Description |
Lactobacillus delbrueckii is an anaerobic, Gram positive, non-motile, rod shaped bacterium. It is non-pathogenic.
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External Links |
Taxonomy ID |
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Genome Assembly ID |
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GOLD Organism ID |
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Disease Relevance |
Type 2 diabetes mellitus [ICD-11: 5A11] |
Description |
Lactobacillus delbrueckii was associated with type 2 diabetes. |
[1] |
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Host Immune Factors (HIFs) |
Interferon-12 subunit alpha |
HIF ID |
HIFM0130 |
HIF Info
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Class |
Cytokine (Cyt) |
Description |
Lactobacillus delbrueckii subsp.lactis CNRZ327 modulated the production of IL-12 in colonic tissue during colitis. |
[2] |
Transforming growth factor beta-2 proprotein |
HIF ID |
HIFM0213 |
HIF Info
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Class |
Cytokine (Cyt) |
Description |
Lactobacillus delbrueckii could modulate the production of TGF-beta in the spleen. |
[2] |
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Environmental Factor(s) |
Disbiome ID |
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gutMDisorder ID |
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References |
1 |
Global metabolic interaction network of the human gut microbiota for context-specific community-scale analysis. Nat Commun. 2017 Jun 6;8:15393. doi: 10.1038/ncomms15393.
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2 |
Local and systemic immune mechanisms underlying the anti-colitis effects of the dairy bacterium Lactobacillus delbrueckii. PLoS One. 2014 Jan 21;9(1):e85923. doi: 10.1371/journal.pone.0085923. eCollection 2014.
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