General Information of MIC (ID: MIC01192)
MIC Name Solobacterium moorei (firmicutes)
MIC Synonyms unclassified Clostridium group RCA59
Body Site Gut
Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Erysipelotrichia
Order: Erysipelotrichales
Family: Erysipelotrichaceae
Genus: Solobacterium
Species: Solobacterium moorei
Oxygen Sensitivity Obligate anaerobe
Microbial Metabolism Saccharolytic; Fermentative
Gram Positive
Genome Size (bp) 2008551
No. of Coding Genes 2035
No. of Non-Coding Genes 95
No. of Small Non-Coding Genes 95
No. of Gene Transcripts 2130
No. of Base Pairs 2008551
Description Solobacterium moorei is a non-spore-forming strict anaerobic Gram-positive bacillus initially isolated from human feces and recognized with the use of 16S rRNA gene sequencing.
External Links Taxonomy ID
102148
Genome Assembly ID
ASM18694v2
GOLD Organism ID
Go0005521
Disease Relevance
          Diseases of coronary artery  [ICD-11: BA8Z]
             Description Solobacterium moorei was associated with genetic variants in Colorectal cancer. [1]
Host Immune Factors (HIFs)
          Neutrophils
             HIF ID HIFC0029 HIF Info       Class Granulocytes (Gra)
             Description Solobacterium moorei at neutrophil recovery was positively correlated with subsequent acute severe graft-versus-host disease. [2]
          Immunoglobulin Y
             HIF ID HIFM0274 HIF Info       Class Immunoglobulin (Ig)
             Description the specific IgY could decrease the bacterial level after infection with Solobacterium moorei. [3]
Environmental Factor(s)
             Disbiome ID
      1511
             gutMDisorder ID
      gm0610
References
1 M-GWAS for the gut microbiome in Chinese adults illuminates on complex diseases. bioRxiv, 2019.
2 Stool Microbiota at Neutrophil Recovery Is Predictive for Severe Acute Graft vs Host Disease After Hematopoietic Cell Transplantation.Clin Infect Dis. 2017 Nov 29;65(12):1984-1991. doi: 10.1093/cid/cix699.
3 Chicken egg yolk antibody (IgY) controls Solobacterium moorei under in vitro and in vivo conditions. Appl Biochem Biotechnol. 2012 Nov;168(6):1448-58. doi: 10.1007/s12010-012-9869-3. Epub 2012 Sep 12.

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