General Information of MIC (ID: MIC01227)
MIC Name	Staphylococcus xylosus (firmicutes)
Body Site	Skin
Lineage	Kingdom: Bacteria Phylum: Firmicutes Class: Bacilli Order: Bacillales Family: Staphylococcaceae Genus: Staphylococcus Species: Staphylococcus xylosus
Oxygen Sensitivity	Facultative anaerobe
Microbial Metabolism	Saccharolytic; Respiratory or Fermentative
Gram	Positive
Genome Size (bp)	2786686
No. of Coding Genes	2512
No. of Non-Coding Genes	78
No. of Small Non-Coding Genes	78
No. of Gene Transcripts	2591
No. of Pseudogenes	1
No. of Base Pairs	2757557
Description	Staphylococcus xylosus is a species of facultatively anaerobic, Gram positive, coagulase negative bacterium. The bacteriumis is a commensal of the skin of humans and animals and a ubiquitous bacterium naturally present in food.
External Links	Taxonomy ID	1288
	Genome Assembly ID	ASM70941v1
	GOLD Organism ID	Go0044260
Disease Relevance
Multiple system atrophy  [ICD-11: 8D87]
Description	Staphylococcus xylosus increased in patients with multiple system atrophy.				[1]

Host Immune Factors (HIFs)
Interleukin-17A
HIF ID	HIFM0134	HIF Info	Class	Cytokine (Cyt)
Description	Staphylococcus xylosus could increase the IL-17A expression.				[2]
CD4+ regulatory T cells
HIF ID	HIFC0034	HIF Info	Class	T cells (TCs)
Description	Staphylococcus xylosus could increase CD4+ T cells responses.				[2]

Environmental Factor(s)
Disbiome ID			1581
gutMDisorder ID			gm0621

References
1	Alterations of the Gut Microbiota in Multiple System Atrophy Patients. Front Neurosci. 2019 Oct 18;13:1102. doi: 10.3389/fnins.2019.01102. eCollection 2019.
2	The resident pathobiont Staphylococcus xylosus in Nfkbiz-deficient skin accelerates spontaneous skin inflammation. Sci Rep. 2017 Jul 24;7(1):6348. doi: 10.1038/s41598-017-05740-z.

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