General Information of MIC (ID: MIC01235)
MIC Name	Streptobacillus moniliformis (fusobacteria)
MIC Synonyms	Haverhillia moniliformis
Body Site	Blood
Lineage	Kingdom: Bacteria Phylum: Fusobacteria Class: Fusobacteriia Order: Fusobacteriales Family: Leptotrichiaceae Genus: Streptobacillus Species: Streptobacillus moniliformis
Oxygen Sensitivity	Facultative anaerobe
Microbial Metabolism	Saccharolytic; Fermentative
Gram	Variable
Host Relationship	Pathogen
Genome Size (bp)	1673280
Description	Streptobacillus moniliformis is a facultatively anaerobic, pleomorphic, Gram-variable bacillus often seen in chains and as long unbranched filaments. It is the causative agent of Rat Bite Fever.
External Links	Taxonomy ID	34105
	Genome Assembly ID	ASM2456v1
	GOLD Organism ID	Go0499611
Disease Relevance
Rat-bite fevers  [ICD-11: 1B90]
Description	Streptobacillus moniliformis can cause rat-bite fever with reactive arthritides.				[1]

Host Immune Factors (HIFs)
Immunoglobulin G2
HIF ID	HIFM0268	HIF Info	Class	Immunoglobulin (Ig)
Description	Streptobacillus moniliformis was associated with IgG2b response.				[2]
Immunoglobulin G1
HIF ID	HIFM0269	HIF Info	Class	Immunoglobulin (Ig)
Description	Streptobacillus moniliformis was associated with IgG2b response.				[2]
CD4+ helper T cells
HIF ID	HIFC0068	HIF Info	Class	T cells (TCs)
Description	Streptobacillus moniliformis is associated with T-helper type 1 cellsTh1) responses.				[2]

Environmental Factor(s)
Disbiome ID			841

References
1	Streptobacillus moniliformis septic arthritis: a clinical entity distinct from rat-bite fever. BMC Infect Dis. 2007 Jun 11;7:56. doi: 10.1186/1471-2334-7-56.
2	Comparative analysis of clinics, pathologies and immune responses in BALB/c and C57BL/6 mice infected with Streptobacillus moniliformis. Microbes Infect. 2018 Feb;20(2):101-110. doi: 10.1016/j.micinf.2017.10.001. Epub 2017 Oct 10.

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