Details of Microbe Species (MIC)

General Information of MIC (ID: MIC01758)
MIC Name Francisella tularensis (gamma-proteobacteria)
MIC Synonyms Bacterium tularense
Body Site Skin
Lineage Kingdom: Bacteria
Phylum: Proteobacteria
Class: Gammaproteobacteria
Order: Thiotrichales
Family: Francisellaceae
Genus: Francisella
Species: Francisella tularensis
Oxygen Sensitivity Aerobe
Microbial Metabolism Respiratory
Gram Negative
Host Relationship Pathogen
Genome Size (bp) 1887196
No. of Coding Genes 2083
No. of Non-Coding Genes 39
No. of Small Non-Coding Genes 39
No. of Gene Transcripts 2122
No. of Base Pairs 1887196
Description Francisella tularensis is a pathogenic species of Gram-negative coccobacillus, an aerobic bacterium. It is nonspore-forming, nonmotile, and the causative agent of tularemia, the pneumonic form of which is often lethal without treatment. It is a fastidious, facultative intracellular bacterium, which requires cysteine for growth.
External Links Taxonomy ID
263
Genome Assembly ID
ASM74201v1
GOLD Organism ID
Go0167295
Host Genetic Factors (HGFs)
          hsa-miR-874-5p
             HGF ID HGF0578 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The expression of hsa-miR-874-5p was up-regulated 1.56-fold in Francisella tularensis. [1]
          hsa-miR-579-5p
             HGF ID HGF0568 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The expression of hsa-miR-579-5p was up-regulated 2.52-fold in Francisella tularensis. [1]
          hsa-miR-5586-3p
             HGF ID HGF0566 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The expression of hsa-miR-5586-3p was up-regulated 3.03-fold in Francisella tularensis. [1]
          hsa-miR-485-5p
             HGF ID HGF0556 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The expression of hsa-miR-485-5p was 3.26-fold down-regulation in Francisella tularensis. [1]
          hsa-miR-4802-3p
             HGF ID HGF0554 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The expression of miR-4802 was 2.52-fold up-regulation in Francisella tularensis. [1]
          hsa-miR-4523
             HGF ID HGF0546 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The expression of miR-4523 was 2.51-fold down-regulated in Francisella tularensis. [1]
          hsa-miR-3909
             HGF ID HGF0545 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The expression of miR-3909 was 1.63-fold up-regulated in Francisella tularensis. [1]
          hsa-miR-3667-3p
             HGF ID HGF0540 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The expression of miR-3667 was 1.56-fold up-regulated in Francisella tularensis. [1]
          hsa-miR-323b-3p
             HGF ID HGF0536 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The expression of miR-323b was 3.03-fold up-regulated in Francisella tularensis. [1]
          hsa-miR-2964a-3p
             HGF ID HGF0534 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The expression of miR-2964a was 2.85-fold up-regulated in Francisella tularensis. [1]
          hsa-miR-125b-5p
             HGF ID HGF0278 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The expression of miR-125b-5p was 2.33-fold up-regulated in Francisella tularensis. [1]
          hsa-miR-154-5p
             HGF ID HGF0244 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The expression of hsa-miR-154-5p was 1.65-fold up-regulated in Francisella tularensis. [1]
          hsa-miR-424-3p
             HGF ID HGF0131 HGF Info       Class Non-coding RNA: Micro (ncRNA-miRNA)
             Description The expression of hsa-miR-424-3p was 1.18-fold up-regulated in Francisella tularensis. [1]
Host Immune Factors (HIFs)
          Immunoglobulin M
             HIF ID HIFM0266 HIF Info       Class Immunoglobulin (Ig)
             Description IgM could provide a component of protective immunity in Franciscella tularensis infection. [2]
References
1 Differential MicroRNA Analyses of Burkholderia pseudomallei- and Francisella tularensis-Exposed hPBMCs Reveal Potential Biomarkers. Int J Genomics. 2017;2017:6489383. doi: 10.1155/2017/6489383. Epub 2017 Jul 16.
2 IgM in microbial infections: taken for granted. Immunol Lett. 2009 Aug 15;125(2):79-85. doi: 10.1016/j.imlet.2009.06.003. Epub 2009 Jun 17.

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