General Information of HGF (ID: HGF0278)
HGF Name	hsa-miR-125b-5p
HGF Synonym(s)	microRNA 125b-5p, MIRN125b-5p, MIR125b-5p
Source	Homo sapiens
HGF Classification	Non-coding RNA: Micro (ncRNA-miRNA)
Gene Location	chr11
Gene Start Site	122099809	Gene End Site		122099830
Strand	Reverse (-)
Sequence	Click here to download the HGF sequence in FASTA format
External Links
	miRBase ID	MIMAT0000423

Microbe Species (MIC) Regulated by This HGF
Brucella sp. (alpha-proteobacteria)			MIC00274
Description	The expression of miR-125b-5p was significantly down-regulated in macrophages during Brucella spp.(Brucella abortus) infection (p-value<0.05).				[1]
Francisella tularensis (gamma-proteobacteria)			MIC01758
Description	The expression of miR-125b-5p was 2.33-fold up-regulated in Francisella tularensis.				[2]
Mycobacterium tuberculosis (actinobacteria)			MIC00857
Description	The level of miR-125b expression showed significantly upregulated in Mycobacterium tuberculosis infection (p-value<0.05).				[3]
Salmonella enterica (enterobacteria)			MIC01150
Description	The level of miR-125b-5p expression showed significantly upregulated upon Salmonella enterica infection (p-value<0.05).				[4]

References
1	Altered serum microRNAs as biomarkers for the early diagnosis of pulmonary tuberculosis infection. Qi Y, Cui L, Ge Y, Shi Z, Zhao K, Guo X, Yang D, Yu H, Cui L, Shan Y, Zhou M, Wang H, Lu Z.. BMC Infect Dis. 2012 Dec 28;12:384. doi: 10.1186/1471-2334-12-384.
2	Differential MicroRNA Analyses of Burkholderia pseudomallei- and Francisella tularensis-Exposed hPBMCs Reveal Potential Biomarkers. Int J Genomics. 2017;2017:6489383. doi: 10.1155/2017/6489383. Epub 2017 Jul 16.
3	Mammalian microRNAs and long noncoding RNAs in the host-bacterial pathogen crosstalk. Semin Cell Dev Biol. 2017 May;65:11-19. doi: 10.1016/j.semcdb.2016.06.016. Epub 2016 Jul 2.
4	Multifaceted Roles of microRNAs in Host-Bacterial Pathogen Interaction. Microbiol Spectr. 2019 May;7(3). doi: 10.1128/microbiolspec.BAI-0002-2019.

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