General Information of HGF (ID: HGF0251)
HGF Name	hsa-miR-146b-5p
HGF Synonym(s)	microRNA 146b-5p, MIRN146b-5p, MIR146b-5p
Source	Homo sapiens
HGF Classification	Non-coding RNA: Micro (ncRNA-miRNA)
Gene Location	chr10
Gene Start Site	102436520	Gene End Site		102436542
Strand	Forward (+)
Sequence	Click here to download the HGF sequence in FASTA format
External Links
	miRBase ID	MIMAT0002809

Microbe Species (MIC) Regulated by This HGF
Listeria monocytogenes (firmicutes)			MIC00771
Description	The level of miR-146b expression showed significantly upregulated upon Listeria monocytogenes infection (p-value<0.05).				[1]
Porphyromonas gingivalis (CFB bacteria)			MIC01000
Description	The miR-146b expression was 4-fold up-regulation by Porphyromonas gingivalis in human gingival fibroblasts.				[2]
Salmonella enterica subsp. enterica (enterobacteria)			MIC01154
Description	The miR-146b-5p presents in mesenteric lymph nodes in Salmonella Typhimurium infected pigs.				[3]
Salmonella sp. (enterobacteria)			MIC01149
Description	hsa-miR-146b-5p miRNA that strongly increase the relative abundance of Salmonella by at least 1.5-fold. The average percentage of Salmonella infection cells(fold over control) is equal to 1.5346.				[4]

References
1	Multifaceted Roles of microRNAs in Host-Bacterial Pathogen Interaction. Microbiol Spectr. 2019 May;7(3). doi: 10.1128/microbiolspec.BAI-0002-2019.
2	MicroRNA-146 inhibits pro-inflammatory cytokine secretion through IL-1 receptor-associated kinase 1 in human gingival fibroblasts. J Inflamm (Lond). 2013 May 16;10(1):20. doi: 10.1186/1476-9255-10-20.
3	Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhimurium infection. Vet Res. 2018 Feb 1;49(1):9. doi: 10.1186/s13567-018-0506-1.
4	Effects of Lactobacillus acidophilus and Bifidobacterium bifidum Probiotics on the Expression of MicroRNAs 135b, 26b, 18a and 155, and Their Involving Genes in Mice Colon Cancer. Heydari Z, Rahaie M, Alizadeh AM, Agah S, Khalighfard S, Bahmani S.. Probiotics Antimicrob Proteins. 2019 Dec;11(4):1155-1162. doi: 10.1007/s12602-018-9478-8.

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