General Information of HGF (ID: HGF0259)
HGF Name	hsa-miR-141-3p
HGF Synonym(s)	microRNA 141-3p, MIRN141-3p, MIR141-3p
Source	Homo sapiens
HGF Classification	Non-coding RNA: Micro (ncRNA-miRNA)
Gene Location	chr12
Gene Start Site	6964155	Gene End Site		6964176
Strand	Forward (+)
Sequence	Click here to download the HGF sequence in FASTA format
External Links
	miRBase ID	MIMAT0000432

Microbe Species (MIC) Regulated by This HGF
Bacteroides acidifaciens (CFB bacteria)			MIC00145
Description	The abundance of the Bacteroides acidifaciens was correlated with the level of miR-141-3p (p-value<0.05).				[1]
Bacteroidetes (CFB bacteria)			MIC00141
Description	The level of miR-141c-3p expression was significantly associated with Bacteroidetes abundances (p-value<0.05).				[2]
Escherichia coli (enterobacteria)			MIC00516
Description	The miR-141 expression showed 1.32-fold down-regulation by Escherichia coli infection.				[3]
Lactobacillus johnsonii (firmicutes)			MIC00721
Description	The expression of hsa-miR-141-3p was decreased with the absence of Lactobacillus johnsonii.				[4]
Porphyromonas gingivalis (CFB bacteria)			MIC01000
Description	The hsa-miR-141-3p was 4-fold up-regulation by Porphyromonas gingivalis in human gingival fibroblasts.				[5]

References
1	Current understanding of the gut microbiota shaping mechanisms.J Biomed Sci. 2019 Aug 21;26(1):59. doi: 10.1186/s12929-019-0554-5.
2	Vascular microRNA-204 is remotely governed by the microbiome and impairs endothelium-dependent vasorelaxation by downregulating Sirtuin1. Vikram A, Kim YR, Kumar S, Li Q, Kassan M, Jacobs JS, Irani K.. Nat Commun. 2016 Sep 2;7:12565. doi: 10.1038/ncomms12565.
3	Whole blood-derived microRNA signatures in mice exposed to lipopolysaccharides. J Biomed Sci. 2012 Jul 31;19(1):69. doi: 10.1186/1423-0127-19-69.
4	Impact of the gut microbiome on the genome and epigenome of colon epithelial cells: contributions to colorectal cancer development. Genome Med. 2019 Feb 25;11(1):11. doi: 10.1186/s13073-019-0621-2.
5	MicroRNA-146 inhibits pro-inflammatory cytokine secretion through IL-1 receptor-associated kinase 1 in human gingival fibroblasts. J Inflamm (Lond). 2013 May 16;10(1):20. doi: 10.1186/1476-9255-10-20.

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