General Information of HGF (ID: HGF0649)
HGF Name hsa-miR-142-5p
HGF Synonym(s) microRNA 142-5p, MIRN142-5p, MIR142-5p
Source Homo sapiens
HGF Classification Non-coding RNA: Micro (ncRNA-miRNA)
Gene Location chr17
Gene Start Site 58331283 Gene End Site 58331303
Strand Reverse (-)
Sequence Click here to download the HGF sequence in FASTA format
External Links
miRBase ID
MIMAT0000433
Microbe Species (MIC) Regulated by This HGF
         Brucella sp. (alpha-proteobacteria) MIC00274
             Description The miR-142-5p was 1.25-fold up-regulated during Brucella infection and differentially expressed (p-value=1.86E-307). [1]
         Helicobacter pylori (epsilon-proteobacteria) MIC00669
             Description The levels of miR-142-5p expression was significantly reduced after Helicobacter pylori eradication. [2]
         Salmonella enterica subsp. enterica (enterobacteria) MIC01154
             Description The miR-142-5p presents in mesenteric lymph nodes in Salmonella Typhimurium infected pigs. [3]
         Salmonella sp. (enterobacteria) MIC01149
             Description hsa-miR-142-5p miRNA that strongly increase the relative abundance of Salmonella by at least 1.5-fold. The average percentage of Salmonella infection cells(fold over control) is equal to 1.7999. [4]
References
1 Transcriptome microRNA profiling of bovine mammary epithelial cells challenged with Escherichia coli or Staphylococcus aureus bacteria reveals pathogen directed microRNA expression profiles. Jin W, Ibeagha-Awemu EM, Liang G, Beaudoin F, Zhao X, Guan le L.. BMC Genomics. 2014 Mar 7;15:181. doi: 10.1186/1471-2164-15-181.
2 miR-143 inhibits intracellular salmonella growth by targeting ATP6V1A in macrophage cells in pig. Huang T, Huang X, Yao M.. Res Vet Sci. 2018 Apr;117:138-143. doi: 10.1016/j.rvsc.2017.12.006. Epub 2017 Dec 15.
3 Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhimurium infection. Vet Res. 2018 Feb 1;49(1):9. doi: 10.1186/s13567-018-0506-1.
4 Effects of Lactobacillus acidophilus and Bifidobacterium bifidum Probiotics on the Expression of MicroRNAs 135b, 26b, 18a and 155, and Their Involving Genes in Mice Colon Cancer. Heydari Z, Rahaie M, Alizadeh AM, Agah S, Khalighfard S, Bahmani S.. Probiotics Antimicrob Proteins. 2019 Dec;11(4):1155-1162. doi: 10.1007/s12602-018-9478-8.

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