| General Information of HGF (ID: HGF1290) |
| HGF Name |
rs5743618
|
| Source |
Homo sapiens
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| HGF Classification |
Single Nucleotide Polymorphism: Missense variant (SNP-MV)
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| Gene Location |
chr4:38797027
|
| SNP in Gene |
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| Microbe Species (MIC) Regulated by This HGF |
|
Corynebacteriales (actinobacteria)
|
MIC00842
|
| Description |
The rs5743618 was associated with the thatoptimal mycobacterial TLR2 signaling. |
[1] |
|
Tannerella forsythia (CFB bacteria)
|
MIC01305
|
| Description |
The rs5743618 SNP was significantly associated with the abundance of Tannerella forsythia (p-value=0.002). |
[2] |
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Treponema denticola (spirochetes)
|
MIC01322
|
| Description |
The rs5743618 SNP was significantly associated with the abundance of Treponema denticola (p-value=0.001). |
[2] |
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| References |
| 1 |
Cystic fibrosis CFBE41o- cells contain TLR1 SNP I602S and fail to respond to Mycobacterium abscessus.J Cyst Fibros. 2013 Dec;12(6):773-9. doi: 10.1016/j.jcf.2013.01.001. Epub 2013 Feb 9.
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| 2 |
Associations of Toll-Like Receptor and -Defensin Polymorphisms with Measures of Periodontal Disease (PD) in HIV+ North American Adults: An Exploratory Study.PLoS One. 2016 Oct 11;11(10):e0164075. doi: 10.1371/journal.pone.0164075. eCollection 2016.
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