General Information of HGF (ID: HGF2312)
HGF Name	CYP27B1
HGF Synonym(s)	VDR, CP2B, CYP1, PDDR, VDD1, VDDR, VDDRI, CYP27B, P450c1, CYP1alpha, cytochrome P450 family 27 subfamily B member 1
Source	Homo sapiens
HGF Classification	Copy Number Variation: Gene Deletion (CNV-GDe)
Gene Location	chr12
Gene Start Site	57762334	Gene End Site		57768986
Strand	Reverse (-)
External Links
	Ensembl ID	ENSG00000111012

Microbe Species (MIC) Regulated by This HGF
Akkermansia muciniphila (verrucomicrobia)			MIC00056
Description	The deletion of CYP27B1 has been significantly associated with the increased amount of Akkermansia muciniphila (p-value<0.01).				[1]
Bacteroides acidifaciens (CFB bacteria)			MIC00145
Description	The deletion of CYP27B1 was significantly decreased the abundance of Bacteroides acidifaciens (p-value<0.05).				[1]
Bacteroides plebeius (CFB bacteria)			MIC00170
Description	The deletion of CYP27B1 was significantly decreased the abundance of Bacteroides plebeius (p-value<0.05).				[1]
Solitalea canadensis (CFB bacteria)			MIC01939
Description	The deletion of CYP27B1 was significantly increased the abundance of Solitalea canadensis (p-value<0.05).				[1]

References
1	1,25(OH)(2)D(3) deficiency-induced gut microbial dysbiosis degrades the colonic mucus barrier in Cyp27b1 knockout mouse model.Gut Pathog. 2019 Feb 20;11:8. doi: 10.1186/s13099-019-0291-z. eCollection 2019.

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