General Information of HGF (ID: HGF2319)
HGF Name	TLR2
HGF Synonym(s)	TIL4, CD282, toll like receptor 2
Source	Homo sapiens
HGF Classification	Copy Number Variation: Gene Deletion (CNV-GDe)
Gene Location	chr4
Gene Start Site	153684070	Gene End Site		153705702
Strand	Forward (+)
External Links
	Ensembl ID	ENSG00000137462

Microbe Species (MIC) Regulated by This HGF
Bacteroidetes (CFB bacteria)			MIC00141
Description	The deletion of TLR2 was significantly associated with a decrease in the Bacteroidetes phyla (p-value<0.05).				[1]
Helicobacter bilis (epsilon-proteobacteria)			MIC00663
Description	The deletion of TLR2 is associated with a decreased abundance of Helicobacter.				[2]
Oscillospira sp. A (firmicutes)			MIC00933
Description	The deletion of TLR2 increased the abundance of Oscillospira.				[1]
Proteobacteria (proteobacteria)			MIC01037
Description	The deletion of TLR2 was significantly associated with a decrease in the Bacteroidetes phyla (p-value<0.05).				[1]
Ruminococcus sp. (firmicutes)			MIC01140
Description	The deletion of TLR2 increased the abundance of Ruminococcus.				[1]

References
1	Microbiota determines insulin sensitivity in TLR2-KO mice.Life Sci. 2019 Oct 1;234:116793. doi: 10.1016/j.lfs.2019.116793. Epub 2019 Aug 26.
2	Current understanding of the gut microbiota shaping mechanisms.J Biomed Sci. 2019 Aug 21;26(1):59. doi: 10.1186/s12929-019-0554-5.

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