General Information of HIF (ID: HIFC0137)
HIF Name	CD20+ B cells
HIF Synonym(s)	(CD)20+ Bcells, CD20+ B cells
HIF Classification	B cells (BCs)
Description	The presence of CXCL13+cells, cluster of differentiation (CD)20+Bcells, CD3+ Tcells, CD138+ plasmacellsand CD35+ follicular dendriticcellswas studied by immunohistochemistry.				[1]

Microbe Species (MIC) Regulated by This HIF
Bifidobacterium sp. (actinobacteria)			MIC00224
Description	Bifidobacterium was negatively correlated with CD20+ B cell counts in the portal tract in patients with simple steatosis.				[2]
Prevotella sp. (CFB bacteria)			MIC01024
Description	Prevotella was negatively correlated with CD20+ B cell in the liver lobule.				[2]
Staphylococcus aureus (firmicutes)			MIC01208
Description	There is no relationship between the numbers of total CD20+ or CD5+CD20+ B cells and the Staphylococcus aureus colonization pattern.				[3]

References
1	Aberrant Humoral Immune Responses in Neurosyphilis: CXCL13/CXCR5 Play a Pivotal Role for B-Cell Recruitment to the Cerebrospinal Fluid.J Infect Dis. 2017 Sep 1;216(5):534-544. doi: 10.1093/infdis/jix233.
2	Markers of activated inflammatory cells are associated with disease severity and intestinal microbiota inadults with nonalcoholic fatty liver disease.Int J Mol Med. 2018 Oct;42(4):2229-2237. doi: 10.3892/ijmm.2018.3800. Epub 2018 Aug 2.
3	Infant B cell memory and gut bacterial colonization.Gut Microbes. 2012 Sep-Oct;3(5):474-5. doi: 10.4161/gmic.21419. Epub 2012 Aug 15.

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