General Information of HIF (ID: HIFC0200)
HIF Name
CD4+FOXP3+ regulatory T cells
HIF Synonym(s)
CD4+ FOXP3+ Tregulatory cells, CD4+FOXP3+ Tregulatory cells
HIF Classification
T cells (TCs)
Description CD4+ FOXP3+ Tregulatory cells is a type of the immune cells. [1]
Microbe Species (MIC) Regulated by This HIF
         Akkermansia muciniphila (verrucomicrobia) MIC00056
             Description Akkermansia muciniphila could increase adipose tissue-resident CD4+ Foxp3+ regulatory T cells. [2]
         Lactobacillus paracasei (firmicutes) MIC00726
             Description Lactobacillus paracasei is related to the increase of CD4+FOXP3+ Treg cells in the MLNs. [3]
         Lactobacillus plantarum (firmicutes) MIC00730
             Description Lactobacillus plantarum DSM15313 is related to the increase of CD4+FOXP3+ Treg cells in the MLNs. [3]
References
1 A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues.PLoS One. 2016 Mar 3;11(3):e0150606. doi: 10.1371/journal.pone.0150606. eCollection 2016.
2 Pili-like proteins of Akkermansia muciniphila modulate host immune responses and gut barrier function. PLoS One. 2017 Mar 1;12(3):e0173004. doi: 10.1371/journal.pone.0173004. eCollection 2017.
3 Development and maintenance of intestinal regulatory T cells.Nat Rev Immunol. 2016 May;16(5):295-309. doi: 10.1038/nri.2016.36. Epub 2016 Apr 18.

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