General Information of HIF (ID: HIFC0219)
HIF Name	IgG plasma B cell
HIF Synonym(s)	IgG plasma cell
HIF Classification	B cells (BCs)
Description	IgG plasma cell is a type of the immune cells.				[1]

Microbe Species (MIC) Regulated by This HIF
Dengue virus (viruses)			MIC02008
Description	IgG plasma cell response was associated with expression of dengue virus.				[2]
Enterovirus C (viruses)			MIC02010
Description	The expression of Poliovirus vaccine could elicited blood IgG plasma cell responses.				[3]
Escherichia coli (enterobacteria)			MIC00516
Description	Enterotoxigenic Escherichia coli (ETEC) vaccine exhibited positive IgG plasma cell responses.				[4]
Human immunodeficiency virus 1 (viruses)			MIC02009
Description	Increased IgG plasma cell was associated with high pH1N1 hemagglutination inhibition responses to the expression of HIV.				[5]
Leishmania infantum (kinetoplastids)			MIC01797
Description	IgG plasma cell were the predominant plasma cells present in the spleens of Visceral leishmaniasis caused by Leishmania infantum.				[6]
Leishmania major (kinetoplastids)			MIC01993
Description	Leishmania stimulated B-cells to differentiate into short-lived IgG plasma cells with limited lifespan in the medullar cords of lymph nodes and splenic red pulp in the primary immune response.				[6]
Lymphocytic choriomeningitis mammarenavirus (viruses)			MIC02006
Description	IgG plasma cell response was associated with the expression of Lymphocytic choriomeningitis virus.				[7]
Plasmodium vivax (apicomplexans)			MIC01998
Description	Plasmodium spp. stimulated B-cells to differentiate into short-lived IgG plasma cells with limited lifespan in the medullar cords of lymph nodes and splenic red pulp in the primary immune response.				[6]
Salmonella sp. (enterobacteria)			MIC01149
Description	Salmonella reduces the number of IgG-secreting plasma cells.				[8]
Unidentified influenza virus (viruses)			MIC02007
Description	IgG plasma cell response was associated with the expression of Influenza virus.				[9]

References
1	A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues.PLoS One. 2016 Mar 3;11(3):e0150606. doi: 10.1371/journal.pone.0150606. eCollection 2016.
2	Total and Envelope Protein-Specific Antibody-Secreting Cell Response in Pediatric Dengue Is Highly Modulated by Age and Subsequent Infections.PLoS One. 2016 Aug 25;11(8):e0161795. doi: 10.1371/journal.pone.0161795. eCollection 2016.
3	Human Circulating Antibody-Producing B Cell as a Predictive Measure of Mucosal Immunity to Poliovirus.PLoS One. 2016 Jan 5;11(1):e0146010. doi: 10.1371/journal.pone.0146010. eCollection 2016.
4	Safety and immunogenicity of a single oral dose of recombinant double mutant heat-labile toxin derived from enterotoxigenic Escherichia coli.Clin Vaccine Immunol. 2013 Nov;20(11):1764-70. doi: 10.1128/CVI.00464-13. Epub 2013 Sep 18.
5	Characterization of functional antibody and memory B-cell responses to pH1N1 monovalent vaccine in HIV-infected children and youth.PLoS One. 2015 Mar 18;10(3):e0118567. doi: 10.1371/journal.pone.0118567. eCollection 2015.
6	Disruption of Splenic Lymphoid Tissue and Plasmacytosis in Canine Visceral Leishmaniasis: Changes in Homing and Survival of Plasma Cells.PLoS One. 2016 May 31;11(5):e0156733. doi: 10.1371/journal.pone.0156733. eCollection 2016.
7	Analyzing Mouse B Cell Responses Specific to LCMV Infection.Methods Mol Biol. 2018;1707:15-38. doi: 10.1007/978-1-4939-7474-0_2.
8	Salmonella SiiE prevents an efficient humoral immune memory by interfering with IgG(+) plasma cell persistence in the bone marrow.Proc Natl Acad Sci U S A. 2019 Apr 9;116(15):7425-7430. doi: 10.1073/pnas.1818242116. Epub 2019 Mar 25.
9	Kinetics of antibody response to influenza vaccination in renal transplant recipients.Transpl Immunol. 2019 Apr;53:51-60. doi: 10.1016/j.trim.2019.01.001. Epub 2019 Jan 18.

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