Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFM0196)
HIF Name
Retinoic acid receptor responder protein2
HIF Synonym(s)
Chemerin, retinoic acid receptor responder protein 2, RARRES2, TIG2
HIF Classification
Antimicrobial peptide (AMP)
Description Chemerin has been identified in humans. It forms the first line of host defense against pathogenic infections and are a key component of the ancient innate immune system. [1]
Sequence Click here to download the HIF sequence in FASTA format
External Links
Uniprot ID
RARR2_HUMAN
APD ID
AP02201
Microbe Species (MIC) Regulated by This HIF
         Fusobacterium nucleatum (fusobacteria) MIC00617
             Description Fusobacterium nucleatum is sensitive to chemerin. [2]
         Porphyromonas gingivalis (CFB bacteria) MIC01000
             Description Gingipains secreted by the periodontopathogen Porphyromonas gingivalis inactivate chemerin. [2]
         Tannerella forsythia (CFB bacteria) MIC01305
             Description There was a significant positive correlation between chemerin gene expression and abundance of Tannerella forsythia. [2]
References
1 APD3: the antimicrobial peptide database as a tool for research and education.Nucleic Acids Res. 2016 Jan 4;44(D1):D1087-93. doi: 10.1093/nar/gkv1278. Epub 2015 Nov 23.
2 Antimicrobial and Attractant Roles for Chemerin in the Oral Cavity during Inflammatory Gum Disease.Front Immunol. 2017 Mar 29;8:353. doi: 10.3389/fimmu.2017.00353. eCollection 2017.

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