General Information of HIF (ID: HIFM0199)
HIF Name	Human resistin
HIF Synonym(s)	Hretn, ADSF
HIF Classification	Antimicrobial peptide (AMP)
Molecular Function	Hormone
Description	hRETN has been identified in humans. It forms the first line of host defense against pathogenic infections and are a key component of the ancient innate immune system.				[1]
Pfam	Resistin (PF06954 )
Sequence	Click here to download the HIF sequence in FASTA format
External Links
	Uniprot ID	RETN_HUMAN
	APD ID	AP03085

Microbe Species (MIC) Regulated by This HIF
Bacteroides thetaiotaomicron (CFB bacteria)			MIC00179
Description	Bacteroides thetaiotaomicron was resistant to hRETN.				[2]
Citrobacter rodentium (enterobacteria)			MIC00366
Description	The viability of Citrobacter rodentium declined 90% decline in viability after a 2-h exposure to 10M hRETN.				[2]
Enterococcus faecalis (firmicutes)			MIC00548
Description	Enterococcus faecalis was resistant to hRETN.				[2]
Staphylococcus epidermidis (firmicutes)			MIC01214
Description	The skin commensal Staphylococcus epidermidis was susceptible to hRETN.				[3]

References
1	APD3: the antimicrobial peptide database as a tool for research and education.Nucleic Acids Res. 2016 Jan 4;44(D1):D1087-93. doi: 10.1093/nar/gkv1278. Epub 2015 Nov 23.
2	Resistin-like molecule is a bactericidal protein that promotes spatial segregation of the microbiota and the colonic epithelium.Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11027-11033. doi: 10.1073/pnas.1711395114. Epub 2017 Sep 25.
3	Seeing Is Believing: Vitamin A Promotes Skin Health through a Host-Derived Antibiotic.Cell Host Microbe. 2019 Jun 12;25(6):769-770. doi: 10.1016/j.chom.2019.05.011.

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