Details of Host Immune Factor (HIF) Regulating Microbe Species (MIC)

General Information of HIF (ID: HIFM0242)
HIF Name
Macrophage inflammatory protein 1
HIF Synonym(s)
MIP2, Macrophage inflammatory protein 2
HIF Classification
Cytokine (Cyt)
Description Macrophage inflammatory protein 1 (MIP-1) is a monocyte-, neutrophil- and lymphocyte-derived CC chemokine family member with inflammatory and chemokinetic properties 1, 2 [1]
Pfam WD domain, G-beta repeat (PF00400 )
Sequence Click here to download the HIF sequence in FASTA format
External Links
Uniprot ID
WDR26_HUMAN
Microbe Species (MIC) Regulated by This HIF
         Bifidobacterium catenulatum (actinobacteria) MIC00211
             Description Bifidobacterium catenulatum and Bifidobacterium breve were the strongest enhancers of interferon-gamma (IFN-gamma) production by direct stimulation of peripheral blood mononuclear cells (PBMC). [2]
         Bifidobacterium pseudocatenulatum (actinobacteria) MIC00219
             Description Bifidobacterium pseudocatenulatum could decrease MIP-1Alpha. [3]
         Clostridioides difficile (firmicutes) MIC00396
             Description Clostridium difficile toxin could induce the production of MIP-2. [4]
         Cyanobacteria (cyanobacteria) MIC00475
             Description At the phylum level, Cyanobacteria is associated with MIP-2. [5]
         Klebsiella aerogenes (enterobacteria) MIC00530
             Description The abundance of Enterobacter aerogenes is associated with MIP-1Alpha. [6]
References
1 Transcriptional regulation of CXC-ELR chemokines KC and MIP-2 in mouse pancreatic acini.Am J Physiol Gastrointest Liver Physiol. 2010 Oct;299(4):G867-76. doi: 10.1152/ajpgi.00177.2010. Epub 2010 Jul 29.
2 Immunostimulatory effect of faecal Bifidobacterium species of breast-fed and formula-fed infants in a peripheral blood mononuclear cell/Caco-2 co-culture system. Br J Nutr. 2011 Oct;106(8):1216-23. doi: 10.1017/S0007114511001656. Epub 2011 May 31.
3 Bifidobacterium pseudocatenulatum LI09 and Bifidobacterium catenulatum LI10 attenuate D-galactosamine-induced liver injury by modifying the gut microbiota. Sci Rep. 2017 Aug 18;7(1):8770. doi: 10.1038/s41598-017-09395-8.
4 Intestinal antimicrobial peptides during homeostasis, infection, and disease.Front Immunol. 2012 Oct 9;3:310. doi: 10.3389/fimmu.2012.00310. eCollection 2012.
5 Lipopolysaccharides from Microcystis Cyanobacteria-Dominated Water Bloom and from Laboratory Cultures Trigger Human Immune Innate Response. Toxins (Basel). 2019 Apr 11;11(4):218. doi: 10.3390/toxins11040218.
6 Immunological cross-reactivity between Enterobacter aerogenes and Klebsiella capsular polysaccharides. Microb Pathog. 1990 Aug;9(2):127-30. doi: 10.1016/0882-4010(90)90086-6.

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