Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00219)
MIC Name Bifidobacterium pseudocatenulatum (actinobacteria)
Body Site Gut
Lineage Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinobacteria
Order: Bifidobacteriales
Family: Bifidobacteriaceae
Genus: Bifidobacterium
Species: Bifidobacterium pseudocatenulatum
Oxygen Sensitivity Obligate anaerobe
Microbial Metabolism Saccharolytic; Fermentative
Gram Positive
Host Relationship Commensal
Genome Size (bp) 1243786
No. of Coding Genes 986
No. of Non-Coding Genes 34
No. of Small Non-Coding Genes 34
No. of Gene Transcripts 1042
No. of Pseudogenes 22
No. of Base Pairs 1243786
Description Bifidobacterium pseudocatenulatuan is a obligate anaerobic,Gram positive member of the Actinobacteria division of the domain bacteria and has been isolated from human faeces. Molecular analyses have shown that members of the Bifidobacterium catenulatum group (which includes B.catenulatum and B. pseudocatenulatum) are abundant in faecal samples from adult humans. B. pseudocatenulatum strains have a number of proboitic properties, such as the capacity to reduce cholesterol levels.
External Links Taxonomy ID
28026
Genome Assembly ID
ASM157688v1
GOLD Organism ID
Go0493777
Disease Relevance
          Dermatitis and eczema  [ICD-11: EA80]
             Description Bifidobacterium pseudocatenulatuan was associated with atopic eczema. [1]
          Irritable bowel syndrome  [ICD-11: DD91]
             Description Bifidobacterium pseudocatenulatum was significantly depleted during dysenteric diarrhea regardless of the etiological agent. [2]
Host Genetic Factors (HGFs)
          rs651821
             HGF ID HGF1924 HGF Info       Class Single Nucleotide Polymorphism: Prime UTR variant (SNP-PV)
             Description The APOA5 SNP rs651821 might be an important host genetic factor in determining the abundances of the health-promoting Bifidobacterium bacteria and the taxa to which this genus belongs. [3]
Host Immune Factors (HIFs)
          C-C motif chemokine 2
             HIF ID HIFM0022 HIF Info       Class Cytokine (Cyt)
             Description Bifidobacterium pseudocatenulatum could decrease MCP-1 expression. [4]
          Macrophage inflammatory protein 1-beta
             HIF ID HIFM0032 HIF Info       Class Cytokine (Cyt)
             Description Bifidobacterium pseudocatenulatum could decrease the MIP-3Alpha expression. [4]
          Macrophage colony-stimulating factor 1
             HIF ID HIFM0065 HIF Info       Class Cytokine (Cyt)
             Description Bifidobacterium pseudocatenulatum could decrease the expression of M-CSF. [4]
          Interferon-10
             HIF ID HIFM0128 HIF Info       Class Cytokine (Cyt)
             Description Bifidobacterium pseudocatenulatum could increase the expression of IL-10. [4]
          Interleukin-1 beta
             HIF ID HIFM0138 HIF Info       Class Cytokine (Cyt)
             Description Bifidobacterium pseudocatenulatum significantly alleviated the D-GalN-induced increase in the proinflammatory cytokine interleukin (IL)-1. [4]
          Macrophage inflammatory protein 1
             HIF ID HIFM0242 HIF Info       Class Cytokine (Cyt)
             Description Bifidobacterium pseudocatenulatum could decrease MIP-1Alpha. [4]
Environmental Factor(s)
             Disbiome ID
      785
             gutMDisorder ID
      gm0113
References
1 Bifidobacterium pseudocatenulatum is associated with atopic eczema: a nested case-control study investigating the fecal microbiota of infants. J Allergy Clin Immunol. 2008 Jan;121(1):135-40. doi: 10.1016/j.jaci.2007.07.061. Epub 2007 Sep 27.
2 Assessing gut microbiota perturbations during the early phase of infectious diarrhea in Vietnamese children. Gut Microbes. 2018 Jan 2;9(1):38-54. doi: 10.1080/19490976.2017.1361093. Epub 2017 Aug 24.
3 The effect of heritability and host genetics on the gut microbiota and metabolic syndrome.Gut. 2017 Jun;66(6):1031-1038. doi: 10.1136/gutjnl-2015-311326. Epub 2016 Apr 6.
4 Bifidobacterium pseudocatenulatum LI09 and Bifidobacterium catenulatum LI10 attenuate D-galactosamine-induced liver injury by modifying the gut microbiota. Sci Rep. 2017 Aug 18;7(1):8770. doi: 10.1038/s41598-017-09395-8.

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