Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00211)
MIC Name Bifidobacterium catenulatum (actinobacteria)
Body Site Gut
Lineage Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinobacteria
Order: Bifidobacteriales
Family: Bifidobacteriaceae
Genus: Bifidobacterium
Species: Bifidobacterium catenulatum
Oxygen Sensitivity Obligate anaerobe
Microbial Metabolism Saccharolytic; Fermentative
Gram Positive
Host Relationship Commensal
Genome Size (bp) 2079525
Description Bifidobacterium catenulatum is a species of obligate anaerobic, Gram positive bacteria. It has been proven to be an effective treatment for acute liver injury.
External Links Taxonomy ID
1686
Genome Assembly ID
ASM17345v1
GOLD Organism ID
Go0539021
Disease Relevance
          Coeliac disease  [ICD-11: DA95]
             Description Bifidobacterium catenulatum prevalence was higher in biopsies of controls than in those of active and non-active coeliac disease patients. [1]
          Irritable bowel syndrome  [ICD-11: DD91]
             Description Quantity of Bifidobacterium catenulatum significantly decreased in faecal and duodenal samples of irritable bowel syndrome patients than healthy control. [2]
Host Genetic Factors (HGFs)
          rs651821
             HGF ID HGF1924 HGF Info       Class Single Nucleotide Polymorphism: Prime UTR variant (SNP-PV)
             Description The APOA5 SNP rs651821 might be an important host genetic factor in determining the abundances of the health-promoting Bifidobacterium bacteria and the taxa to which this genus belongs. [3]
Host Immune Factors (HIFs)
          C-C motif chemokine 2
             HIF ID HIFM0022 HIF Info       Class Cytokine (Cyt)
             Description Bifidobacterium catenulatum is associated with the MCP-1 expression. [4]
          Macrophage colony-stimulating factor 1
             HIF ID HIFM0065 HIF Info       Class Cytokine (Cyt)
             Description Bifidobacterium catenulatum is associated with the expression of M-CSF. [4]
          Interferon-10
             HIF ID HIFM0128 HIF Info       Class Cytokine (Cyt)
             Description Bifidobacterium catenulatum can enhance the interferon- (IFN-) production by direct stimulation of peripheral blood mononuclear cells (PBMC). [4]
          Interleukin-1 beta
             HIF ID HIFM0138 HIF Info       Class Cytokine (Cyt)
             Description Bifidobacterium catenulatum could stimulate the IL-1beta secretion. [4]
          Macrophage inflammatory protein 1
             HIF ID HIFM0242 HIF Info       Class Cytokine (Cyt)
             Description Bifidobacterium catenulatum and Bifidobacterium breve were the strongest enhancers of interferon-gamma (IFN-gamma) production by direct stimulation of peripheral blood mononuclear cells (PBMC). [4]
          Interferon gamma
             HIF ID HIFM0260 HIF Info       Class Cytokine (Cyt)
             Description Bifidobacterium catenulatum can enhance IFN-Gamma production. [4]
Environmental Factor(s)
             Disbiome ID
      38
             gutMDisorder ID
      gm0110
References
1 Imbalances in faecal and duodenal Bifidobacterium species composition in active and non-active coeliac disease. BMC Microbiol. 2008 Dec 22;8:232. doi: 10.1186/1471-2180-8-232.
2 The gut microbiota and irritable bowel syndrome: friend or foe. Int J Inflam. 2012;2012:151085. doi: 10.1155/2012/151085. Epub 2012 Apr 22.
3 The effect of heritability and host genetics on the gut microbiota and metabolic syndrome.Gut. 2017 Jun;66(6):1031-1038. doi: 10.1136/gutjnl-2015-311326. Epub 2016 Apr 6.
4 Immunostimulatory effect of faecal Bifidobacterium species of breast-fed and formula-fed infants in a peripheral blood mononuclear cell/Caco-2 co-culture system. Br J Nutr. 2011 Oct;106(8):1216-23. doi: 10.1017/S0007114511001656. Epub 2011 May 31.

If you find any error in data or bug in web service, please kindly report it to Dr. Tang and Dr. Mou.