| General Information of MIC (ID: MIC00256) |
| MIC Name |
Borrelia turicatae (spirochaetes)
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| MIC Synonyms |
Spirochaeta turicatae
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| Body Site |
Blood
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| Lineage |
Kingdom: Bacteria
Phylum: Spirochaetes
Class: Spirochaetia
Order: Spirochaetales
Family: Borreliaceae
Genus: Borrelia
Species: Borrelia turicatae
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| Oxygen Sensitivity |
Aerobe
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| Microbial Metabolism |
Respiration
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| Gram |
Negative
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| Description |
Borrelia turicatae is a bacterial species of the spirochaete class of the genus Borrelia. It is a Gram-negative bacterium and visible with light microscopy.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| GOLD Organism ID |
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| Host Genetic Factors (HGFs) |
| rs41289586 |
| HGF ID |
HGF1927 |
HGF Info
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Class |
Single Nucleotide Polymorphism: Missense variant (SNP-MV) |
| Description |
The rs41289586 SNP was significantly associated with the abundance of Borrelia turicatae (p-value=7.18E-08). |
[1] |
| rs17850869 |
| HGF ID |
HGF1225 |
HGF Info
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Class |
Single Nucleotide Polymorphism: Synonymous variant (SNP-SV) |
| Description |
The rs17850869 SNP was significantly associated with the abundance of Borrelia turicatae (p-value=4.17E-09). |
[1] |
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| Host Immune Factors (HIFs) |
| B cells |
| HIF ID |
HIFC0001 |
HIF Info
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Class |
B cells (BCs) |
| Description |
A global decline in peripheral B-cell populations was observed at 14 days postinfection of Borrelia turicatae. |
[2] |
| Interleukin-1 beta |
| HIF ID |
HIFM0138 |
HIF Info
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Class |
Cytokine (Cyt) |
| Description |
Borrelia turicatae induced significant increases expression in IL-1beta. |
[2] |
| Tumor necrosis factor |
| HIF ID |
HIFM0226 |
HIF Info
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Class |
Cytokine (Cyt) |
| Description |
Borrelia turicatae elicits from peripheral blood cells key inflammatory response mediators (interleukin-1Beta and tumor necrosis factor alpha), which are associated with preterm abortion. |
[2] |
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| Environmental Factor(s) |
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| References |
| 1 |
A Coding Variant of ANO10, Affecting Volume Regulation of Macrophages, Is Associated with Borrelia Seropositivity.Mol Med. 2015 Feb 23;21(1):26-37. doi: 10.2119/molmed.2014.00219.
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| 2 |
Immunological Responses to the Relapsing Fever Spirochete Borrelia turicatae in Infected Rhesus Macaques: Implications for Pathogenesis and Diagnosis. Infect Immun. 2019 Mar 25;87(4):e00900-18. doi: 10.1128/IAI.00900-18. Print 2019 Apr.
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