| General Information of MIC (ID: MIC00455) |
| MIC Name |
Corynebacterium glutamicum (actinobacteria)
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| MIC Synonyms |
Micrococcus glutamicus
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| Body Site |
Ocular Surface
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| Lineage |
Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinobacteria
Order: Corynebacteriales
Family: Corynebacteriaceae
Genus: Corynebacterium
Species: Corynebacterium glutamicum
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| Oxygen Sensitivity |
Anaerobe
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| Microbial Metabolism |
Fermentative
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| Gram |
Positive
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| Genome Size (bp) |
3293729
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| No. of Coding Genes |
2760
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| No. of Non-Coding Genes |
76
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| No. of Small Non-Coding Genes |
76
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| No. of Gene Transcripts |
2836
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| No. of Base Pairs |
3162487
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| Description |
Corynebacterium glutamicum is a small, non-moving Gram-positive soil bacterium. Physically, it is rod shaped with the ends swelled in a shape similar to a club.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| Host Immune Factors (HIFs) |
| T-cell surface glycoprotein CD1b |
| HIF ID |
HIFM0039 |
HIF Info
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Class |
Checkpoint molecule (CM) |
| Description |
CD1b dextramers loaded with either pure synthetic PGs matching the common mammalian form Corynebacterium glutamicum. |
[1] |
| Macrophages |
| HIF ID |
HIFC0020 |
HIF Info
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Class |
Macrophages (Mac) |
| Description |
Cell wall extracts of Corynebacterium glutamicum stimulated the inflammatory response of macrophages in a dose-dependent manner. |
[2] |
| Toll-like receptor 2 |
| HIF ID |
HIFM0217 |
HIF Info
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Class |
Toll-like receptor (TLR) |
| Description |
TLR2 but not TLR4 seems to be critical for sensing cell wall extracts from Corynebacterium glutamicum by primary macrophages. |
[2] |
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| Environmental Factor(s) |
| Disbiome ID |
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| gutMDisorder ID |
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| References |
| 1 |
Human autoreactive T cells recognize CD1b and phospholipids.Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):380-5. doi: 10.1073/pnas.1520947112. Epub 2015 Nov 30.
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| 2 |
The role of corynomycolic acids in Corynebacterium-host interaction. Antonie Van Leeuwenhoek. 2018 May;111(5):717-725. doi: 10.1007/s10482-018-1036-6. Epub 2018 Feb 12.
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