| General Information of MIC (ID: MIC00764) |
| MIC Name |
Leuconostoc citreum (firmicutes)
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| MIC Synonyms |
Leuconostoc amelibiosum
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| Body Site |
Gut
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| Lineage |
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Leuconostocaceae
Genus: Leuconostoc
Species: Leuconostoc citreum
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| Oxygen Sensitivity |
Anaerobe
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| Microbial Metabolism |
Fermentive
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| Gram |
Positive
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| Description |
Leuconostoc citreum is a vancomycin-resistant, Gram-positive, anaerobic, coccus-shaped bacterium.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| GOLD Organism ID |
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| Host Genetic Factors (HGFs) |
| rs1129942 |
| HGF ID |
HGF1898 |
HGF Info
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Class |
Single Nucleotide Polymorphism: Missense variant (SNP-MV) |
| Description |
The rs1129942 SNP was significantly associated with the abundance of Leuconostoc (p-value=9.63E-05). |
[1] |
| rs11188353 |
| HGF ID |
HGF1329 |
HGF Info
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Class |
Single Nucleotide Polymorphism: Intron variant (SNP-IV) |
| Description |
The rs11188353 SNP was significantly associated with the relative abundance of Leuconostoc (p-value=1.04E-08). |
[2] |
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| Host Immune Factors (HIFs) |
| Interferon-12 subunit alpha |
| HIF ID |
HIFM0130 |
HIF Info
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Class |
Cytokine (Cyt) |
| Description |
The ability of Leuconostoc citreum to stimulate IFN-gamma was dependent on its induction of IL-12 expression. |
[3] |
| Mast cells |
| HIF ID |
HIFC0022 |
HIF Info
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Class |
Granulocytes (Gra) |
| Description |
Leuconostoc citreum is associated with mast cells response. |
[3] |
| Macrophages |
| HIF ID |
HIFC0020 |
HIF Info
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Class |
Macrophages (Mac) |
| Description |
Leuconostoc citreum HJ-P4 induces interleukin-12 through nuclear factor-kappa B and p38/c-Jun N-terminal kinases signaling in macrophages. |
[3] |
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| Environmental Factor(s) |
| Disbiome ID |
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| gutMDisorder ID |
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| References |
| 1 |
Whole exome sequencing analyses reveal gene-microbiota interactions in the context of IBD.Gut. 2020 Jul 10:gutjnl-2019-319706. doi: 10.1136/gutjnl-2019-319706. Online ahead of print.
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| 2 |
Association of host genome with intestinal microbial composition in a large healthy cohort.Nat Genet. 2016 Nov;48(11):1413-1417. doi: 10.1038/ng.3693. Epub 2016 Oct 3.
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| 3 |
Leuconostoc citreum isolated from kimchi suppresses the development of collagen-induced arthritis in DBA/1 mice. Min-SungKwon. Journal of Functional Foods. 63, 103579. doi:10.1016/j.jff.2019.103579
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