| General Information of MIC (ID: MIC01023) |
| MIC Name |
Prevotella salivae (CFB bacteria)
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| Body Site |
Oral Cavity
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| Lineage |
Kingdom: Bacteria
Phylum: Bacteroidetes
Class: Bacteroidia
Order: Bacteroidales
Family: Prevotellaceae
Genus: Prevotella
Species: Prevotella salivae
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| Oxygen Sensitivity |
Anaerobe
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| Microbial Metabolism |
Saccharolytic; Fermentative
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| Gram |
Negative
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| Host Relationship |
Commensal
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| Genome Size (bp) |
3140543
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| Description |
Prevotella salivae is an anaerobic, Gram negative bacterium. It was found over-represented in endodontic infection samples.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| GOLD Organism ID |
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| Disease Relevance |
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| Periodontal disease [ICD-11: DA0C] |
| Description |
Prevotella salivae was over-represented in samples with endodontic infections. |
[1] |
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| Host Immune Factors (HIFs) |
| Interferon-10 |
| HIF ID |
HIFM0128 |
HIF Info
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Class |
Cytokine (Cyt) |
| Description |
Prevotella salivae reduced the production of IL10 cytokines in monocyte derived dendritic cells. |
[2] |
| Interleukin-23 subunit alpha |
| HIF ID |
HIFM0144 |
HIF Info
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Class |
Cytokine (Cyt) |
| Description |
Prevotella salivae stimulate the release of IL23 by dendritic cells (DC) through Tolllike receptor 2. |
[2] |
| IL-12 subunit p70 |
| HIF ID |
HIFM0264 |
HIF Info
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Class |
Cytokine (Cyt) |
| Description |
Prevotella salivae could decrease IL-12p70. |
[2] |
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| Environmental Factor(s) |
| Disbiome ID |
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| References |
| 1 |
Microbial transformation from normal oral microbiota to acute endodontic infections. BMC Genomics. 2012 Jul 28;13:345. doi: 10.1186/1471-2164-13-345.
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| 2 |
The immune response to Prevotella bacteria in chronic inflammatory disease. Immunology. 2017 Aug;151(4):363-374. doi: 10.1111/imm.12760. Epub 2017 Jun 20.
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