Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00502)
MIC Name Desulfovibrio vulgaris (delta-proteobacteria)
Body Site Gut
Lineage Kingdom: Bacteria
Phylum: Proteobacteria
Class: Deltaproteobacteria
Order: Desulfovibrionales
Family: Desulfovibrionaceae
Genus: Desulfovibrio
Species: Desulfovibrio vulgaris
Oxygen Sensitivity Anaerobe
Microbial Metabolism Oxidative
Gram Negative
Genome Size (bp) 3773159
Description Desulfovibrio vulgaris is a Gram-negative, anaerobic, non-spore forming, curved rod-shaped bacterium, that can be found in soil, animal intestines and feces. Desulfovibrio vulgaris is ubiquitous in nature and has also been implicated in a variety of human bacterial infections, although it may only be an opportunistic pathogen.
External Links Taxonomy ID
881
Genome Assembly ID
ASM1548v1
GOLD Organism ID
Go0234101
Host Immune Factors (HIFs)
          Interferon gamma
             HIF ID HIFM0260 HIF Info       Class Cytokine (Cyt)
             Description Desulfovibrio vulgaris triggerd nitric oxide production at levels similar to those stimulated by the cytokine gamma interferon (IFN-). [1]
          M1 macrophages
             HIF ID HIFC0019 HIF Info       Class Macrophages (Mac)
             Description The ratio of M1/M2 colonic macrophage was greatly increased by the Desulfovibrio vulgaris. [2]
          Macrophages
             HIF ID HIFC0020 HIF Info       Class Macrophages (Mac)
             Description The Desulfovibrio vulgaris wild-type strain suffered an approximately 30% decrease in survival upon coculture with macrophages(P< 0.005). [1]
          M2 macrophages
             HIF ID HIFC0124 HIF Info       Class Macrophages (Mac)
             Description The ratio of M1/M2 colonic macrophage was greatly increased by the Desulfovibrio vulgaris. [2]
Environmental Factor(s)
             Disbiome ID
      2
             gutMDisorder ID
      gm0256
References
1 Hybrid cluster proteins and flavodiiron proteins afford protection to Desulfovibrio vulgaris upon macrophage infection. J Bacteriol. 2013 Jun;195(11):2684-90. doi: 10.1128/JB.00074-13. Epub 2013 Apr 5.
2 Glabridin Prevents Doxorubicin-Induced Cardiotoxicity Through Gut Microbiota Modulation and Colonic Macrophage Polarization in Mice.Front Pharmacol. 2019 Feb 15;10:107. doi: 10.3389/fphar.2019.00107. eCollection 2019.

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