General Information of MIC (ID: MIC00528)
MIC Name Entamoeba histolytica (eukaryotes)
Body Site Gut
Lineage Kingdom: Eukaryota
Phylum: Evosea
Class: Archamoebae
Order: Mastigamoebida
Family: Entamoebidae
Genus: Entamoeba
Species: Entamoeba histolytica
Description Entamoeba histolytica is an anaerobic parasitic amoebozoan.
External Links Taxonomy ID
5759
Genome Assembly ID
Ehistolytica_2016
GOLD Organism ID
Go0038929
Host Immune Factors (HIFs)
          Mouse bone marrow-derived dendritic cells
             HIF ID HIFC0005 HIF Info       Class Dendritic cells (DCs)
             Description Bone marrow-derived dendritic cells from mouse was sufficient to provide protection against Entamoeba histolytica. [1]
          Immunoglobulin A
             HIF ID HIFM0272 HIF Info       Class Immunoglobulin (Ig)
             Description Entamoeba histolytica trophozoites could degrade the level of human IgA and result in the low IgA concentration. [2]
          Immunoglobulin A1
             HIF ID HIFM0275 HIF Info       Class Immunoglobulin (Ig)
             Description Entamoeba histolytica trophozoites could degrade the level of human IgA1 and result in the low IgA1 concentration. [2]
          Immunoglobulin A2
             HIF ID HIFM0276 HIF Info       Class Immunoglobulin (Ig)
             Description Entamoeba histolytica trophozoites could degrade the level of human IgA2 and result in the low IgA2 concentration. [2]
References
1 Bone marrow dendritic cells from mice with an altered microbiota provide interleukin 17A-dependent protection against Entamoeba histolytica colitis.mBio. 2014 Nov 4;5(6):e01817. doi: 10.1128/mBio.01817-14.
2 Degradation of human secretory IgA1 and IgA2 by Entamoeba histolytica surface-associated proteolytic activity.Parasitol Int. 2008 Dec;57(4):417-23. doi: 10.1016/j.parint.2008.04.013. Epub 2008 May 15.

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