General Information of MIC (ID: MIC00528) |
MIC Name |
Entamoeba histolytica (eukaryotes)
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Body Site |
Gut
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Lineage |
Kingdom: Eukaryota
Phylum: Evosea
Class: Archamoebae
Order: Mastigamoebida
Family: Entamoebidae
Genus: Entamoeba
Species: Entamoeba histolytica
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Description |
Entamoeba histolytica is an anaerobic parasitic amoebozoan.
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External Links |
Taxonomy ID |
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Genome Assembly ID |
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GOLD Organism ID |
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Host Immune Factors (HIFs) |
Mouse bone marrow-derived dendritic cells |
HIF ID |
HIFC0005 |
HIF Info
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Class |
Dendritic cells (DCs) |
Description |
Bone marrow-derived dendritic cells from mouse was sufficient to provide protection against Entamoeba histolytica. |
[1] |
Immunoglobulin A |
HIF ID |
HIFM0272 |
HIF Info
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Class |
Immunoglobulin (Ig) |
Description |
Entamoeba histolytica trophozoites could degrade the level of human IgA and result in the low IgA concentration. |
[2] |
Immunoglobulin A1 |
HIF ID |
HIFM0275 |
HIF Info
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Class |
Immunoglobulin (Ig) |
Description |
Entamoeba histolytica trophozoites could degrade the level of human IgA1 and result in the low IgA1 concentration. |
[2] |
Immunoglobulin A2 |
HIF ID |
HIFM0276 |
HIF Info
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Class |
Immunoglobulin (Ig) |
Description |
Entamoeba histolytica trophozoites could degrade the level of human IgA2 and result in the low IgA2 concentration. |
[2] |
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References |
1 |
Bone marrow dendritic cells from mice with an altered microbiota provide interleukin 17A-dependent protection against Entamoeba histolytica colitis.mBio. 2014 Nov 4;5(6):e01817. doi: 10.1128/mBio.01817-14.
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2 |
Degradation of human secretory IgA1 and IgA2 by Entamoeba histolytica surface-associated proteolytic activity.Parasitol Int. 2008 Dec;57(4):417-23. doi: 10.1016/j.parint.2008.04.013. Epub 2008 May 15.
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