General Information of MIC (ID: MIC00595)
MIC Name	Filifactor alocis (firmicutes)
MIC Synonyms	Fusobacterium alocis
Body Site	Oral Cavity
Lineage	Kingdom: Bacteria Phylum: Firmicutes Class: Clostridia Order: Clostridiales Family: Peptostreptococcaceae Genus: Filifactor Species: Filifactor alocis
Oxygen Sensitivity	Obligate anaerobe
Microbial Metabolism	Fermentative
Gram	Negative
Genome Size (bp)	1931012
Description	Filifactor alocis is characterized as rod shaped, Gram negative, obligate anaerobe and it is a none spore forming bacterium.
External Links	Taxonomy ID	143361
	Genome Assembly ID	ASM16389v2
	GOLD Organism ID	Go0003912

Host Immune Factors (HIFs)
Interleukin-1 beta
HIF ID	HIFM0138	HIF Info	Class	Cytokine (Cyt)
Description	Filifactor alocis elicited a local inflammatory response with an increase in levels of the proinflammatory cytokines interleukin 1 (IL-1).				[1]
Interferon-6
HIF ID	HIFM0151	HIF Info	Class	Cytokine (Cyt)
Description	Filifactor alocis elicited a local inflammatory response with neutrophils along with an increase in levels of IL-6.				[1]
Tumor necrosis factor
HIF ID	HIFM0226	HIF Info	Class	Cytokine (Cyt)
Description	Filifactor alocis could elicite a local inflammatory response along with an increase in levels of tumor necrosis factor (TNF).				[1]
Neutrophils
HIF ID	HIFC0029	HIF Info	Class	Granulocytes (Gra)
Description	Massive neutrophil infiltration was observed in the spleen and lungs infected by Filifactor alocis, and the recruited neutrophils were in close proximity to the infecting bacteria.				[1]

Environmental Factor(s)
Disbiome ID			347
gutMDisorder ID			gm0330

References
1	Filifactor alocis infection and inflammatory responses in the mouse subcutaneous chamber model. Infect Immun. 2014 Mar;82(3):1205-12. doi: 10.1128/IAI.01434-13. Epub 2013 Dec 30.

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