| General Information of MIC (ID: MIC00872) |
| MIC Name |
Mycoplasma hyopneumoniae (mycoplasmas)
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| MIC Synonyms |
Mycoplasma suipneumoniae
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| Body Site |
Lung
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| Lineage |
Kingdom: Bacteria
Phylum: Tenericutes
Class: Mollicutes
Order: Mycoplasmatales
Family: Mycoplasmataceae
Genus: Mycoplasma
Species: Mycoplasma hyopneumoniae
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| Oxygen Sensitivity |
Facultative anaerobe
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| Microbial Metabolism |
Saccharolytic; Fermentative
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| Gram |
Positive
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| Genome Size (bp) |
897405
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| Description |
Mycoplasma hyopneumoniae is a species of bacteria known to cause the disease porcine enzootic pneumonia, a highly contagious and chronic disease affecting pigs.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| GOLD Organism ID |
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| Disease Relevance |
|---|
| Pneumonia [ICD-11: CA40] |
| Description |
M. hyopneumoniae ability can cause porcine enzootic pneumonia. |
[1] |
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| Host Immune Factors (HIFs) |
| B cells |
| HIF ID |
HIFC0001 |
HIF Info
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Class |
B cells (BCs) |
| Description |
Mycoplasma hyopneumoniae promoted the class-switch recombination of B cells to produce IgA under the help of dendritic cells. |
[2] |
| Immunoglobulin A |
| HIF ID |
HIFM0272 |
HIF Info
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Class |
Immunoglobulin (Ig) |
| Description |
Toll-like receptor 2 (TLR2) and TLR4 mediate the IgA immune response induced by Mycoplasma hyopneumoniae. |
[2] |
| Toll-like receptor 2 |
| HIF ID |
HIFM0217 |
HIF Info
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Class |
Toll-like receptor (TLR) |
| Description |
Tlr2 mediated the IgA immune response induced by Mycoplasma hyopneumoniae. |
[2] |
| Toll-like receptor 4 |
| HIF ID |
HIFM0219 |
HIF Info
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Class |
Toll-like receptor (TLR) |
| Description |
Tlr4 mediated the IgA immune response induced by Mycoplasma hyopneumoniae. |
[2] |
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| Environmental Factor(s) |
| Disbiome ID |
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| References |
| 1 |
Secretomes of Mycoplasma hyopneumoniae and Mycoplasma flocculare reveal differences associated to pathogenesis. J Proteomics. 2017 Feb 10;154:69-77. doi: 10.1016/j.jprot.2016.12.002. Epub 2016 Dec 18.
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| 2 |
Toll-Like Receptor 2 (TLR2) and TLR4 Mediate the IgA Immune Response Induced by Mycoplasma hyopneumoniae. Infect Immun. 2019 Dec 17;88(1):e00697-19. doi: 10.1128/IAI.00697-19. Print 2019 Dec 17.
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