General Information of HGF (ID: HGF0177)
HGF Name hsa-miR-29b-3p
HGF Synonym(s) microRNA 29b-3p, MIRN29b-3p, MIR29b-3p
Source Homo sapiens
HGF Classification Non-coding RNA: Micro (ncRNA-miRNA)
Gene Location chr1
Gene Start Site 207802450 Gene End Site 207802472
Strand Reverse (-)
Sequence Click here to download the HGF sequence in FASTA format
External Links
miRBase ID
MIMAT0000100
Microbe Species (MIC) Regulated by This HGF
         Aggregatibacter actinomycetemcomitans (gamma-proteobacteria) MIC00051
             Description The miR-29b was significantly induced down-regulation by Aggregatibacter actinomycetemcomitans (p-value<0.05). [1]
         Lactobacillus reuteri (firmicutes) MIC00731
             Description The level of miR-29b expression was significantly upregulated in binding sites on 16S ribosomal RNA of Lactobacillus reuteri (p-value<0.05). [2]
         Listeria monocytogenes (firmicutes) MIC00771
             Description The expression of hsa-miR-29b-3p was significantly down-regulated by Listeria monocytogenes pathogensa infection (p-value<0.05). [3]
         Porphyromonas gingivalis (CFB bacteria) MIC01000
             Description The level of miR-29b expression was significantly down-regulated by Porphyromonas gingivalis (p-value<0.05). [4]
         Salmonella enterica (enterobacteria) MIC01150
             Description The level of miR-29a expression showed significantly upregulated upon Salmonella enterica infection (p-value<0.05). [3]
References
1 MicroRNAs responsive to Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis LPS modulate expression of genes regulating innate immunity in human macrophages. Innate Immun. 2014 Jul;20(5):540-51. doi: 10.1177/1753425913501914. Epub 2013 Sep 23.
2 Dietary Gluten-Induced Gut Dysbiosis Is Accompanied by Selective Upregulation of microRNAs with Intestinal Tight Junction and Bacteria-Binding Motifs in Rhesus Macaque Model of Celiac Disease. Nutrients. 2016 Oct 28;8(11):684. doi: 10.3390/nu8110684.
3 Multifaceted Roles of microRNAs in Host-Bacterial Pathogen Interaction. Microbiol Spectr. 2019 May;7(3). doi: 10.1128/microbiolspec.BAI-0002-2019.
4 MicroRNAs and immunity in periodontal health and disease. Int J Oral Sci. 2018 Aug 6;10(3):24. doi: 10.1038/s41368-018-0025-y.

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