General Information of HGF (ID: HGF0258)
HGF Name	hsa-miR-143-3p
HGF Synonym(s)	microRNA 143-3p, MIRN143-3p, MIR143-3p
Source	Homo sapiens
HGF Classification	Non-coding RNA: Micro (ncRNA-miRNA)
Gene Location	chr5
Gene Start Site	149428978	Gene End Site		149428998
Strand	Forward (+)
Sequence	Click here to download the HGF sequence in FASTA format
External Links
	miRBase ID	MIMAT0000435

Microbe Species (MIC) Regulated by This HGF
Gardnerella vaginalis (actinobacteria)			MIC00626
Description	The level of miR-143 expression was significantly upregulated by Gardnella vaginalis infection (p-value<0.05).				[1]
Helicobacter pylori (epsilon-proteobacteria)			MIC00669
Description	The level of miR-143-3p expression showed significantly upregulated upon Helicobacter pylori infection (p-value<0.05).				[2]
Listeria monocytogenes (firmicutes)			MIC00771
Description	The level of miR-143 expression was significantly downregulated in the intestines of mice infected with Listeria monocytogenes (p-value<0.05).				[3]
Porphyromonas gingivalis (CFB bacteria)			MIC01000
Description	The hsa-miR-143-3p was 3-fold up-regulation by Porphyromonas gingivalis in human gingival fibroblasts.				[4]
Salmonella enterica subsp. enterica (enterobacteria)			MIC01154
Description	The miR-143-3p presents in mesenteric lymph nodes in Salmonella Typhimurium infected pigs.				[5]
Salmonella sp. (enterobacteria)			MIC01149
Description	The level of miR-143 expression could inhibit intracellular Salmonella growth.				[6]

References
1	Influence of Aspergillus fumigatus conidia viability on murine pulmonary microRNA and mRNA expression following subchronic inhalation exposure. Croston TL, Nayak AP, Lemons AR, Goldsmith WT, Gu JK, Germolec DR, Beezhold DH, Green BJ.. Clin Exp Allergy. 2016 Oct;46(10):1315-27. doi: 10.1111/cea.12783. Epub 2016 Sep 16.
2	Multifaceted Roles of microRNAs in Host-Bacterial Pathogen Interaction. Microbiol Spectr. 2019 May;7(3). doi: 10.1128/microbiolspec.BAI-0002-2019.
3	Gastric Mucosal Microarchitectures Associated with Irreversibility with Helicobacter pylori Eradication and Downregulation of Micro RNA (miR)-124a. Tahara T, Tahara S, Horiguchi N, Kawamura T, Okubo M, Nagasaka M, Nakagawa Y, Shibata T, Urano M, Tsukamoto T, Kuroda M, Ohmiya N.. Cancer Invest. 2019;37(9):417-426. doi: 10.1080/07357907.2019.1663207. Epub 2019 Sep 13.
4	MicroRNA-146 inhibits pro-inflammatory cytokine secretion through IL-1 receptor-associated kinase 1 in human gingival fibroblasts. J Inflamm (Lond). 2013 May 16;10(1):20. doi: 10.1186/1476-9255-10-20.
5	Regulatory role of microRNA in mesenteric lymph nodes after Salmonella Typhimurium infection. Vet Res. 2018 Feb 1;49(1):9. doi: 10.1186/s13567-018-0506-1.
6	The roles of exosomal miRNAs and lncRNAs in lung diseases. Li Y, Yin Z, Fan J, Zhang S, Yang W.. Signal Transduct Target Ther. 2019 Nov 13;4:47. doi: 10.1038/s41392-019-0080-7. eCollection 2019.

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