General Information of HGF (ID: HGF0264)
HGF Name	hsa-miR-135b-5p
HGF Synonym(s)	microRNA 135b-5p, MIRN135b-5p, MIR135b-5p
Source	Homo sapiens
HGF Classification	Non-coding RNA: Micro (ncRNA-miRNA)
Gene Location	chr1
Gene Start Site	205448361	Gene End Site		205448383
Strand	Reverse (-)
Sequence	Click here to download the HGF sequence in FASTA format
External Links
	miRBase ID	MIMAT0000758

Microbe Species (MIC) Regulated by This HGF
Bifidobacterium bifidum (actinobacteria)			MIC00209
Description	The expression of miR-135b was 0.71-fold down-regulation in the plasma samples with Bifidobacterium bifidum infection.				[1]
Burkholderia pseudomallei (beta-proteobacteria)			MIC00287
Description	The expression of hsa-miR-135b-5p was 2.01-fold up-regulated in Burkholderia pseudomallei.				[2]
Fusobacterium nucleatum (fusobacteria)			MIC00617
Description	The abundance of Fusobacterium nucleatum can affect cytokine expression possibly via recognition by TLR4 and TLR2 with regulation by miR-135b.				[3]
Helicobacter pylori (epsilon-proteobacteria)			MIC00669
Description	Helicobacter pylori infection upregulated miR-135b-5p expression through a NF-B-dependent mechanism.				[4]
Lactobacillus acidophilus (firmicutes)			MIC00702
Description	The level of miR-135b expression was 0.56-fold down-regulation in Lactobacillus acidophilus.				[1]

References
1	Expression profiling of peripheral blood miRNA using RNAseq technology in dairy cows with Escherichia coli-induced mastitis. Luoreng ZM, Wang XP, Mei CG, Zan LS.. Sci Rep. 2018 Aug 23;8(1):12693. doi: 10.1038/s41598-018-30518-2.
2	Differential MicroRNA Analyses of Burkholderia pseudomallei- and Francisella tularensis-Exposed hPBMCs Reveal Potential Biomarkers. Int J Genomics. 2017;2017:6489383. doi: 10.1155/2017/6489383. Epub 2017 Jul 16.
3	Relationship between Fusobacterium nucleatum, inflammatory mediators and microRNAs in colorectal carcinogenesis. World J Gastroenterol. 2018 Dec 21;24(47):5351-5365. doi: 10.3748/wjg.v24.i47.5351.
4	Mechanisms of Inflammasome Signaling, microRNA Induction and Resolution of Inflammation by Helicobacter pylori. Curr Top Microbiol Immunol. 2019;421:267-302. doi: 10.1007/978-3-030-15138-6_11.

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