General Information of HGF (ID: HGF2334)
HGF Name	KLB
HGF Synonym(s)	BKL, klotho beta
Source	Homo sapiens
HGF Classification	Copy Number Variation: Gene Deletion (CNV-GDe)
Gene Location	chr4
Gene Start Site	39406930	Gene End Site		39451533
Strand	Forward (+)
External Links
	Ensembl ID	ENSG00000134962

Microbe Species (MIC) Regulated by This HGF
Akkermansia sp. (verrucomicrobia)			MIC00057
Description	The deletion of KLB increased the proportion of Bacteroides.				[1]
Alloprevotella rava (CFB bacteria)			MIC01875
Description	The deletion of KLB increased the proportion of Alloprevotella.				[1]
Bacteroides sp. (CFB bacteria)			MIC00176
Description	The deletion of KLB increased the proportion of Bacteroides.				[1]
Eubacterium coprostanoligenes (firmicutes)			MIC01924
Description	The deletion of KLB increased the proportion of Eubacterium coprostanoligenes.				[1]
Oscillibacter valericigenes (firmicutes)			MIC01961
Description	The deletion of KLB reduced the proportion of Oscillibacter.				[1]
Parabacteroides distasonis (CFB bacteria)			MIC00949
Description	The deletion of KLB increased the proportion of Parabacteroides.				[1]
Rikenella microfusus (CFB bacteria)			MIC01112
Description	The deletion of KLB increased the proportion of Rikenella.				[1]
Ruminococcus sp. (firmicutes)			MIC01140
Description	The deletion of KLB reduced the proportion of Ruminococcus.				[1]

References
1	-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue.JCI Insight. 2017 Apr 20;2(8):e91809. doi: 10.1172/jci.insight.91809. eCollection 2017 Apr 20.

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