General Information of HGF (ID: HGF2355)
HGF Name	NLRP3
HGF Synonym(s)	AVP, FCU, MWS, FCAS, KEFH, CIAS1, FCAS1, NALP3, C1orf7, CLR1.1, DFNA34, PYPAF1, AGTAVPRL, NLR family pyrin domain containing 3
Source	Homo sapiens
HGF Classification	Copy Number Variation: Gene Deletion (CNV-GDe)
Gene Location	chr1
Gene Start Site	247416156	Gene End Site		247449108
Strand	Forward (+)
External Links
	Ensembl ID	ENSG00000162711

Microbe Species (MIC) Regulated by This HGF
Bacteroides sp. (CFB bacteria)			MIC00176
Description	The deletion of NLRP3 could significantly decrease the abundance of Bacteroides (p-value<0.001).				[1]
Desulfovibrio sp. (delta-proteobacteria)			MIC00493
Description	The deletion of NLRP3 could significantly increase the abundance of Desulfovibrio (p-value<0.001).				[1]
Oscillospira sp. A (firmicutes)			MIC00933
Description	The deletion of NLRP3 could significantly increase the abundance of Oscillospira (p-value<0.01).				[1]
Prevotella sp. (CFB bacteria)			MIC01024
Description	The deletion of NLRP3 could significantly increase the abundance of Prevotella (p-value<0.001).				[1]
Ruminococcus sp. (firmicutes)			MIC01140
Description	The deletion of NLRP3 could significantly increase the abundance of Ruminococcus (p-value<0.01).				[1]

References
1	Gut microbiota from NLRP3-deficient mice ameliorates depressive-like behaviors by regulating astrocyte dysfunction via circHIPK2.Microbiome. 2019 Aug 22;7(1):116. doi: 10.1186/s40168-019-0733-3.

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