| General Information of MIC (ID: MIC00245) |
| MIC Name |
Bordetella bronchiseptica (beta-proteobacteria)
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| MIC Synonyms |
Bacillus bronchisepticus
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| Body Site |
Lung
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| Lineage |
Kingdom: Bacteria
Phylum: Proteobacteria
Class: Betaproteobacteria
Order: Burkholderiales
Family: Alcaligenaceae
Genus: Bordetella
Species: Bordetella bronchiseptica
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| Oxygen Sensitivity |
Aerobe
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| Microbial Metabolism |
Saccharolytic; Respiratory
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| Gram |
Negative
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| Genome Size (bp) |
5338656
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| No. of Coding Genes |
4791
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| No. of Non-Coding Genes |
63
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| No. of Small Non-Coding Genes |
63
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| No. of Gene Transcripts |
4854
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| No. of Base Pairs |
5191712
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| Description |
Bordetella bronchiseptica is an aerobic, Gram negative bacterium. It can cause infectious bronchitis in dogs and other animals, but rarely infects humans.
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| External Links |
Taxonomy ID |
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| Genome Assembly ID |
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| GOLD Organism ID |
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| Disease Relevance |
|---|
| Pneumonia [ICD-11: CA40] |
| Description |
Bordetella bronchiseptica was associated with the increased severity of pneumonia. |
[1] |
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| Host Immune Factors (HIFs) |
| C-C motif chemokine 2 |
| HIF ID |
HIFM0022 |
HIF Info
|
Class |
Cytokine (Cyt) |
| Description |
Bordetella bronchiseptica is associated with the MCP-1 expression. |
[2] |
| Interferon gamma |
| HIF ID |
HIFM0260 |
HIF Info
|
Class |
Cytokine (Cyt) |
| Description |
Bordetella bronchiseptica could mediate inhibition of IFN-Gamma production. |
[2] |
| Macrophages |
| HIF ID |
HIFC0020 |
HIF Info
|
Class |
Macrophages (Mac) |
| Description |
Bordetella bronchiseptica is able to modulate cytokine production by macrophages. |
[2] |
| T cells |
| HIF ID |
HIFC0002 |
HIF Info
|
Class |
T cells (TCs) |
| Description |
Relative abundances of Bordetella bronchiseptica is associated with T cells response. |
[2] |
| CD4+CD25+FOXP3+ regulatory T cells |
| HIF ID |
HIFC0036 |
HIF Info
|
Class |
T cells (TCs) |
| Description |
Bordetella bronchiseptica carriage in the respiratory tract was associated with the expansion of Bordetella-specific CD4+CD25+Foxp3+ Treg. |
[2] |
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| References |
| 1 |
Coinfection of pigs with porcine respiratory coronavirus and Bordetella bronchiseptica. Vet Microbiol. 2008 Apr 1;128(1-2):36-47. doi: 10.1016/j.vetmic.2007.09.025. Epub 2007 Oct 12.
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| 2 |
Respiratory Bordetella bronchiseptica Carriage is Associated with Broad Phenotypic Alterations of Peripheral CD4+CD25+ T Cells and Differentially Affects Immune Responses to Secondary Non-Infectious and Infectious Stimuli in Mice. Int J Mol Sci. 2018 Sep 1;19(9):2602. doi: 10.3390/ijms19092602.
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