General Information of MIC (ID: MIC00258)
MIC Name	Brachyspira hyodysenteriae (spirochaetes)
MIC Synonyms	Treponema hyodysenteriae
Body Site	Gut
Lineage	Kingdom: Bacteria Phylum: Spirochaetes Class: Spirochaetia Order: Brachyspirales Family: Brachyspiraceae Genus: Brachyspira Species: Brachyspira hyodysenteriae
Oxygen Sensitivity	Anaerobe
Microbial Metabolism	fermentative
Gram	Negative
Genome Size (bp)	3108081
No. of Coding Genes	2708
No. of Non-Coding Genes	37
No. of Small Non-Coding Genes	37
No. of Gene Transcripts	2745
No. of Base Pairs	3108081
Description	Brachyspira hyodysenteriae is a Gram-negative anaerobic spirochete.
External Links	Taxonomy ID	159
	Genome Assembly ID	ASM101311v1
	GOLD Organism ID	Go0493708

Host Immune Factors (HIFs)
Interferon-10
HIF ID	HIFM0128	HIF Info	Class	Cytokine (Cyt)
Description	Brachyspira colonized mice could secrete higher amounts of IL-10.				[1]
Interferon-4
HIF ID	HIFM0149	HIF Info	Class	Cytokine (Cyt)
Description	The IL-4 concentrations in MLN culture supernatants were significantly (P < 0.05) increased in Brachyspira colonized mice.				[1]
Interferon gamma
HIF ID	HIFM0260	HIF Info	Class	Cytokine (Cyt)
Description	The abundance of Brachyspira bilis may be associated with IFN-Gamma.				[1]
Immunoglobulin G2
HIF ID	HIFM0268	HIF Info	Class	Immunoglobulin (Ig)
Description	Brachyspira infection could increase antigen-specific IgG2a responses to the resident microflora.				[1]
Immunoglobulin G1
HIF ID	HIFM0269	HIF Info	Class	Immunoglobulin (Ig)
Description	Brachyspira infection could increase antigen-specific IgG1 responses to the resident microflora.				[1]

Environmental Factor(s)
Disbiome ID			378

References
1	Induction of differential immune reactivity to members of the flora of gnotobiotic mice following colonization with Helicobacter bilis or Brachyspira hyodysenteriae. Microbes Infect. 2006 May;8(6):1602-10. doi: 10.1016/j.micinf.2006.01.019. Epub 2006 Apr 18.

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