General Information of MIC (ID: MIC00480)
MIC Name	Deltaproteobacteria (delta-proteobacteria)
MIC Synonyms	Myxococcia
Body Site	Oral Cavity
Lineage	Kingdom: Bacteria Phylum: Proteobacteria Class: Deltaproteobacteria
Oxygen Sensitivity	Strictly anaerobe
Microbial Metabolism	Saccharolytic; Fermentative; Sulfur-reducing
Gram	Negative
Description	The Deltaproteobacteria is a class of Proteobacteria. All species of this group are Gram-negative.
External Links	Taxonomy ID	28221
	GOLD Organism ID	Go0528869
Disease Relevance
Periodontal disease  [ICD-11: DA0C]
Description	Deltaproteobacteria had the potential to play a role in the etiology of periodontal disease.				[1]

Host Immune Factors (HIFs)
Interleukin-17A
HIF ID	HIFM0134	HIF Info	Class	Cytokine (Cyt)
Description	Deltaproteobacteria has associations with the IL-17(p = 0.685;R2 = 0.034)in the adipose tissue.				[2]
Interferon-4
HIF ID	HIFM0149	HIF Info	Class	Cytokine (Cyt)
Description	Deltaproteobacteria has associations with the IL-4(p = 0.086;R2 = 0.562)in the heart tissue.				[2]
Interferon-6
HIF ID	HIFM0151	HIF Info	Class	Cytokine (Cyt)
Description	Deltaproteobacteria has associations with the IL-6(p = 490;R2 = 0.070)in the heart tissue.				[2]
Interferon gamma
HIF ID	HIFM0260	HIF Info	Class	Cytokine (Cyt)
Description	Deltaproteobacteria could increase IFN-Gamma.				[2]
Interleukin-1
HIF ID	HIFM0263	HIF Info	Class	Cytokine (Cyt)
Description	Deltaproteobacteria could increase IL-1.				[2]

Environmental Factor(s)
Disbiome ID			624
gutMDisorder ID			gm0249

References
1	Multiple single-cell genomes provide insight into functions of uncultured Deltaproteobacteria in the human oral cavity. PLoS One. 2013;8(3):e59361. doi: 10.1371/journal.pone.0059361. Epub 2013 Mar 26.
2	Gut Dysbiosis and Adaptive Immune Response in Diet-induced Obesity vs. Systemic Inflammation. Front Microbiol. 2017 Jun 22;8:1157. doi: 10.3389/fmicb.2017.01157. eCollection 2017.

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