Details of Microbe Species (MIC)

General Information of MIC (ID: MIC00728)
MIC Name Lactobacillus pentosus (firmicutes)
Body Site Gut
Lineage Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Lactobacillales
Family: Lactobacillaceae
Genus: Lactobacillus
Species: Lactobacillus pentosus
Oxygen Sensitivity Facultative anaerobe
Microbial Metabolism Saccharolytic; Respiratory or Fermentative
Gram Positive
Genome Size (bp) 3426323
Description Lactobacillus pentosus is a facultatively anaerobic, Gram posotive bacterium.
External Links Taxonomy ID
1589
Genome Assembly ID
ASM143375v1
GOLD Organism ID
Go0016336
Disease Relevance
          Inflammatory bowel disease  [ICD-11: DD72]
             Description Lactobacillus pentosus was associated with inflammatory bowel disease. [1]
Host Immune Factors (HIFs)
          Interleukin-27 receptor
             HIF ID HIFM0121 HIF Info       Class Cytokine (Cyt)
             Description Cytokine receptor IL-27R was highly expressed during Lactobacillus pentosus KF340 infection. [2]
          Interferon-10
             HIF ID HIFM0128 HIF Info       Class Cytokine (Cyt)
             Description Lactobacillus pentosus KF340 induced a regulatory phenotype which, in turn, induced IL-10 producing Tr1 cells from naive CD4+ T cells. [2]
          Interferon gamma
             HIF ID HIFM0260 HIF Info       Class Cytokine (Cyt)
             Description Lactobacillus pentosus KF340 induced a regulatory phenotype which, in turn, induced IFN-gamma producing Tr1 cells from naive CD4+ T cells. [2]
          Immunoglobulin E
             HIF ID HIFM0271 HIF Info       Class Immunoglobulin (Ig)
             Description Oral administration of Lactobacillus pentosus KF340 in mice with atopic dermatitis reduced cellular infiltration in affected ear lobes and serum IgE levels. [2]
          Type 1 regulatory T cells
             HIF ID HIFC0032 HIF Info       Class T cells (TCs)
             Description Lactobacillus pentosus modulated immune response by inducing Il-10 producing Tr1 cells(Type 1 regulatory T cells). [2]
Environmental Factor(s)
             Disbiome ID
      1
             gutMDisorder ID
      gm0404
References
1 Probiotic Properties of Lactobacillus Strains Isolated from Table Olive Biofilms. Probiotics Antimicrob Proteins. 2019 Dec 1. doi: 10.1007/s12602-019-09604-y. Online ahead of print.
2 Lactobacillus pentosus Modulates Immune Response by Inducing IL-10 Producing Tr1 Cells. Immune Netw. 2019 Dec 26;19(6):e39. doi: 10.4110/in.2019.19.e39. eCollection 2019 Dec.

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